5OSB

GLIC-GABAAR alpha1 chimera crystallized in complex with THDOC at pH4.5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E (A, B, C, D, E)	Proton-gated ion channel,Gamma-aminobutyric acid receptor subunit alpha-1,Gamma-aminobutyric acid receptor subunit alpha-1	polymer	336	38644.2	5	UniProt (Q7NDN8) UniProt (P62812) Pfam (PF02931) Pfam (PF02932)	Gloeobacter violaceus (strain PCC 7421)	GLIC,Ligand-gated ion channel,LGIC,GABA(A) receptor subunit alpha-1,GABA(A) receptor subunit alpha-1
2	F, G, J, L, P (A, B, C, E)	Tetrahydrodeoxycorticosterone	non-polymer		334.5	5	Chemie (A8Z)
3	H, K, M, N, Q (A, B, C, D, E)	ACETATE ION	non-polymer		59.0	5	Chemie (ACT)
4	I, O (A, D)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)

Sequence modifications

A, B, C, D, E: 1 - 193 (UniProt: Q7NDN8)
A, B, C, D, E: 223 - 311 (UniProt: P62812)

PDB	External Database	Details
Val 258	Gly 285	conflict

A, B, C, D, E: 390 - 428 (UniProt: P62812)

PDB	External Database	Details
Ser 312	-	linker
Gln 313	-	linker
Pro 314	-	linker
Ala 315	-	linker
Arg 316	-	linker
Ala 317	-	linker
Ala 318	-	linker
His 429	-	expression tag
His 430	-	expression tag
His 431	-	expression tag
His 432	-	expression tag
His 433	-	expression tag
His 434	-	expression tag
His 435	-	expression tag
His 436	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	193220.9
Non-Polymers*	Number of molecules	12
	Total formula weight	2038.6
All*	Total formula weight	195259.5

*Water molecules are not included.