5OR9
Crystal Structure of BAZ2B bromodomain in complex with 1-methyl-cyclopentapyrazole compound 13
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bromodomain adjacent to zinc finger domain protein 2B | polymer | 117 | 13618.7 | 1 | UniProt (Q9UIF8) Pfam (PF00439) In PDB | Homo sapiens (Human) | hWALp4 |
| 2 | A | (2~{S})-1-(4-fluorophenyl)sulfonyl-~{N}-(2-methyl-5,6-dihydro-4~{H}-cyclopenta[c]pyrazol-3-yl)pyrrolidine-2-carboxamide | non-polymer | 392.4 | 1 | Chemie (JR5) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A: 1858 - 1972 (UniProt: Q9UIF8)
| PDB | External Database | Details |
|---|---|---|
| Ser 1856 | - | expression tag |
| Met 1857 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13618.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 454.5 | |
| All* | Total formula weight | 14073.2 |
