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5OR9

Crystal Structure of BAZ2B bromodomain in complex with 1-methyl-cyclopentapyrazole compound 13

Functional Information from PDB Data
site_idAC1
Number of Residues12
Detailsbinding site for residue JR5 A 2001
ChainResidue
ALYS1861
AILE1950
AHOH2110
AHOH2138
ATRP1887
APRO1888
APHE1889
ALEU1891
APRO1892
AVAL1893
APHE1943
AASN1944

site_idAC2
Number of Residues1
Detailsbinding site for residue EDO A 2002
ChainResidue
ALYS1896

Functional Information from PROSITE/UniProt
site_idPS00633
Number of Residues58
DetailsBROMODOMAIN_1 Bromodomain signature. AwpFllpvNlklvp..GYKkvIkkpMdfstIreklssgq..Ypnletfaldvrl.VfdNCetF
ChainResidueDetails
AALA1886-PHE1943

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:21406692
ChainResidueDetails
ALEU1918

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692
ChainResidueDetails
ATYR1923

227344

PDB entries from 2024-11-13

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