5OOB

COMPLEX OF HUMAN NUCLEAR CAP-BINDING COMPLEX WITH M7GTP AND NELF-E C-TERMINAL PEPTIDE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, F, I	Nuclear cap-binding protein subunit 1	polymer	772	89781.9	4	UniProt (Q09161) Pfam (PF02854) Pfam (PF09088) Pfam (PF09090) In PDB	Homo sapiens (Human)	80 kDa nuclear cap-binding protein,NCBP 80 kDa subunit
2	B, D, G, J	Nuclear cap-binding protein subunit 2	polymer	158	18156.3	4	UniProt (P52298) Pfam (PF00076) In PDB	Homo sapiens (Human)	20 kDa nuclear cap-binding protein,Cell proliferation-inducing gene 55 protein,NCBP 20 kDa subunit,CBP20,NCBP-interacting protein 1,NIP1
3	E, K, Z	Negative elongation factor E	polymer	21	2507.7	3	UniProt (P18615) UniProt (by SIFTS) (L9KL62) In PDB	Homo sapiens	NELF-E,RNA-binding protein RD
4	B, D, G, J	7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE	non-polymer		539.2	4	Chemie (MGT)

Sequence modifications

A, C, F, I: 20 - 790 (UniProt: Q09161)

PDB	External Database	Details
Met 19	-	initiating methionine

B, D, G, J: 1 - 156 (UniProt: P52298)

PDB	External Database	Details
Gly -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	11
	Total formula weight	439276.0
Non-Polymers*	Number of molecules	4
	Total formula weight	2156.9
All*	Total formula weight	441432.9

*Water molecules are not included.