5OMX

X-ray Structure of the H2A-N38C Nucleosome Core Particle

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	I	DNA (147-MER)	polymer	147	45368.1	1		Homo sapiens (Human)
2	J	DNA (147-MER)	polymer	147	45359.0	1		Homo sapiens (Human)
3	A, E	Histone H3.2	polymer	135	15271.9	2	UniProt (P84233) Pfam (PF00125) In PDB	Xenopus laevis (African clawed frog)
4	B, F	Histone H4	polymer	103	11394.4	2	UniProt (P62799) Pfam (PF15511) In PDB	Xenopus laevis (African clawed frog)
5	C, G	Histone H2A	polymer	129	13967.3	2	UniProt (Q6AZJ8) Pfam (PF00125) Pfam (PF16211) UniProt (by SIFTS) (P06897) In PDB	Xenopus laevis (African clawed frog)
6	D, H	Histone H2B 1.1	polymer	122	13524.8	2	UniProt (P02281) Pfam (PF00125) In PDB	Xenopus laevis (African clawed frog)	H2B1.1
7	I, J, E	MANGANESE (II) ION	non-polymer		54.9	33	Chemie (MN)
8	A, C, E, G	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
9		water	water		18.0	172	Chemie (HOH)

Sequence modifications

A, E: 1 - 135 (UniProt: P84233)

PDB	External Database	Details
Ala 102	Gly 103	conflict
Ala 110	Cys 111	engineered mutation

C, G: 1 - 129 (UniProt: Q6AZJ8)

PDB	External Database	Details
Cys 38	Asn 39	engineered mutation

D, H: 4 - 125 (UniProt: P02281)

PDB	External Database	Details
Thr 32	Ser 33	conflict

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	199043.7
Non-Polymers*	Number of molecules	37
	Total formula weight	1954.8
All*	Total formula weight	200998.5

*Water molecules are not included.