5OMX
X-ray Structure of the H2A-N38C Nucleosome Core Particle
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000786 | cellular_component | nucleosome |
| A | 0003677 | molecular_function | DNA binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005694 | cellular_component | chromosome |
| A | 0030527 | molecular_function | structural constituent of chromatin |
| A | 0046982 | molecular_function | protein heterodimerization activity |
| B | 0000786 | cellular_component | nucleosome |
| B | 0003677 | molecular_function | DNA binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005694 | cellular_component | chromosome |
| B | 0006334 | biological_process | nucleosome assembly |
| B | 0030527 | molecular_function | structural constituent of chromatin |
| B | 0046982 | molecular_function | protein heterodimerization activity |
| C | 0000786 | cellular_component | nucleosome |
| C | 0003677 | molecular_function | DNA binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0005694 | cellular_component | chromosome |
| C | 0030527 | molecular_function | structural constituent of chromatin |
| C | 0046982 | molecular_function | protein heterodimerization activity |
| D | 0000786 | cellular_component | nucleosome |
| D | 0003677 | molecular_function | DNA binding |
| D | 0005515 | molecular_function | protein binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0005694 | cellular_component | chromosome |
| D | 0030527 | molecular_function | structural constituent of chromatin |
| D | 0046982 | molecular_function | protein heterodimerization activity |
| E | 0000786 | cellular_component | nucleosome |
| E | 0003677 | molecular_function | DNA binding |
| E | 0005515 | molecular_function | protein binding |
| E | 0005634 | cellular_component | nucleus |
| E | 0005654 | cellular_component | nucleoplasm |
| E | 0005694 | cellular_component | chromosome |
| E | 0030527 | molecular_function | structural constituent of chromatin |
| E | 0046982 | molecular_function | protein heterodimerization activity |
| F | 0000786 | cellular_component | nucleosome |
| F | 0003677 | molecular_function | DNA binding |
| F | 0005515 | molecular_function | protein binding |
| F | 0005634 | cellular_component | nucleus |
| F | 0005694 | cellular_component | chromosome |
| F | 0006334 | biological_process | nucleosome assembly |
| F | 0030527 | molecular_function | structural constituent of chromatin |
| F | 0046982 | molecular_function | protein heterodimerization activity |
| G | 0000786 | cellular_component | nucleosome |
| G | 0003677 | molecular_function | DNA binding |
| G | 0005634 | cellular_component | nucleus |
| G | 0005694 | cellular_component | chromosome |
| G | 0030527 | molecular_function | structural constituent of chromatin |
| G | 0046982 | molecular_function | protein heterodimerization activity |
| H | 0000786 | cellular_component | nucleosome |
| H | 0003677 | molecular_function | DNA binding |
| H | 0005515 | molecular_function | protein binding |
| H | 0005634 | cellular_component | nucleus |
| H | 0005694 | cellular_component | chromosome |
| H | 0030527 | molecular_function | structural constituent of chromatin |
| H | 0046982 | molecular_function | protein heterodimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue MN I 102 |
| Chain | Residue |
| I | DT33 |
| I | DC34 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue MN I 105 |
| Chain | Residue |
| I | DA54 |
| I | DT55 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue MN I 107 |
| Chain | Residue |
| I | DG-59 |
| I | DC-58 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue MN I 108 |
| Chain | Residue |
| I | DG64 |
| I | DG65 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue MN I 111 |
| Chain | Residue |
| I | DC11 |
| I | DT-68 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue MN I 114 |
| Chain | Residue |
| I | DG48 |
| I | HOH215 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue MN I 115 |
| Chain | Residue |
| I | DG61 |
| I | HOH216 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue MN I 116 |
| Chain | Residue |
| I | DG27 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue MN I 117 |
| Chain | Residue |
| I | DG5 |
| I | HOH207 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue MN I 118 |
| Chain | Residue |
| I | DG-2 |
| I | DG-3 |
| I | HOH217 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue MN I 119 |
| Chain | Residue |
| I | DG-35 |
| I | DG-34 |
| site_id | AD3 |
| Number of Residues | 1 |
| Details | binding site for residue MN J 101 |
| Chain | Residue |
| J | DA-70 |
| site_id | AD4 |
| Number of Residues | 1 |
| Details | binding site for residue MN J 102 |
| Chain | Residue |
| J | DA29 |
| site_id | AD5 |
| Number of Residues | 1 |
| Details | binding site for residue MN J 103 |
| Chain | Residue |
| J | DC11 |
| site_id | AD6 |
| Number of Residues | 1 |
| Details | binding site for residue MN J 104 |
| Chain | Residue |
| J | DC-64 |
| site_id | AD7 |
| Number of Residues | 1 |
| Details | binding site for residue MN J 106 |
| Chain | Residue |
| J | DA66 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue MN J 107 |
| Chain | Residue |
| J | DG64 |
| J | DG65 |
| site_id | AD9 |
| Number of Residues | 2 |
| Details | binding site for residue MN J 108 |
| Chain | Residue |
| J | DG61 |
| J | HOH210 |
| site_id | AE1 |
| Number of Residues | 2 |
| Details | binding site for residue MN J 109 |
| Chain | Residue |
| I | HOH201 |
| J | DG27 |
| site_id | AE2 |
| Number of Residues | 1 |
| Details | binding site for residue MN J 110 |
| Chain | Residue |
| J | DG-3 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue MN J 111 |
| Chain | Residue |
| J | DG48 |
| J | HOH205 |
| J | HOH211 |
| site_id | AE4 |
| Number of Residues | 3 |
| Details | binding site for residue MN J 112 |
| Chain | Residue |
| J | DG-34 |
| J | DG-35 |
| J | HOH208 |
| site_id | AE5 |
| Number of Residues | 1 |
| Details | binding site for residue MN J 113 |
| Chain | Residue |
| J | DG5 |
| site_id | AE6 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 201 |
| Chain | Residue |
| A | PRO121 |
| A | LYS122 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue CL C 201 |
| Chain | Residue |
| C | GLY46 |
| D | THR90 |
| D | SER91 |
| site_id | AE8 |
| Number of Residues | 6 |
| Details | binding site for residue MN E 201 |
| Chain | Residue |
| D | VAL48 |
| D | HOH202 |
| D | HOH211 |
| E | ASP77 |
| E | HOH307 |
| F | HOH216 |
| site_id | AE9 |
| Number of Residues | 2 |
| Details | binding site for residue CL E 202 |
| Chain | Residue |
| E | PRO121 |
| E | LYS122 |
| site_id | AF1 |
| Number of Residues | 6 |
| Details | binding site for residue CL G 201 |
| Chain | Residue |
| G | GLY44 |
| G | ALA45 |
| G | GLY46 |
| G | ALA47 |
| H | THR90 |
| H | SER91 |
Functional Information from PROSITE/UniProt
| site_id | PS00046 |
| Number of Residues | 7 |
| Details | HISTONE_H2A Histone H2A signature. AGLqFPV |
| Chain | Residue | Details |
| C | ALA21-VAL27 |
| site_id | PS00047 |
| Number of Residues | 5 |
| Details | HISTONE_H4 Histone H4 signature. GAKRH |
| Chain | Residue | Details |
| B | GLY14-HIS18 |
| site_id | PS00322 |
| Number of Residues | 7 |
| Details | HISTONE_H3_1 Histone H3 signature 1. KAPRKQL |
| Chain | Residue | Details |
| A | LYS14-LEU20 |
| site_id | PS00357 |
| Number of Residues | 23 |
| Details | HISTONE_H2B Histone H2B signature. REIQTavRlLLpGELaKHAVSEG |
| Chain | Residue | Details |
| D | ARG92-GLY114 |
| site_id | PS00959 |
| Number of Residues | 9 |
| Details | HISTONE_H3_2 Histone H3 signature 2. PFqRLVREI |
| Chain | Residue | Details |
| A | PRO66-ILE74 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250 |
| Chain | Residue | Details |
| C | SER1 | |
| G | SER1 | |
| D | LYS15 | |
| D | LYS20 | |
| H | LYS5 | |
| H | LYS12 | |
| H | LYS15 | |
| H | LYS20 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250 |
| Chain | Residue | Details |
| C | LYS5 | |
| G | LYS5 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:P0C0S8 |
| Chain | Residue | Details |
| C | LYS9 | |
| C | LYS95 | |
| G | LYS9 | |
| G | LYS95 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-(2-hydroxyisobutyryl)lysine; alternate => ECO:0000250|UniProtKB:P0C0S8 |
| Chain | Residue | Details |
| C | LYS36 | |
| G | LYS36 | |
| H | LYS120 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-(2-hydroxyisobutyryl)lysine => ECO:0000250|UniProtKB:P0C0S8 |
| Chain | Residue | Details |
| C | LYS74 | |
| C | LYS75 | |
| G | LYS74 | |
| G | LYS75 | |
| F | LYS8 | |
| F | LYS16 | |
| F | LYS44 | |
| F | LYS79 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: N5-methylglutamine => ECO:0000250 |
| Chain | Residue | Details |
| C | GLN104 | |
| G | GLN104 | |
| F | LYS12 | |
| F | LYS20 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-glutaryllysine; alternate => ECO:0000250|UniProtKB:P0C0S8 |
| Chain | Residue | Details |
| C | LYS118 | |
| G | LYS118 | |
| F | LYS31 | |
| F | LYS91 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 8 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250 |
| Chain | Residue | Details |
| C | LYS13 | |
| F | SER47 | |
| C | LYS15 | |
| C | LYS119 | |
| G | LYS13 | |
| G | LYS15 | |
| G | LYS119 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P62805 |
| Chain | Residue | Details |
| B | TYR51 | |
| B | TYR88 | |
| F | TYR51 | |
| F | TYR88 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-glutaryllysine; alternate => ECO:0000250|UniProtKB:P62805 |
| Chain | Residue | Details |
| B | LYS59 | |
| E | LYS64 | |
| F | LYS59 | |
| A | LYS27 | |
| A | LYS36 | |
| A | LYS64 | |
| E | LYS18 | |
| E | LYS23 | |
| E | LYS27 | |
| E | LYS36 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:P62805 |
| Chain | Residue | Details |
| B | LYS77 | |
| F | LYS77 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in UFM1); alternate => ECO:0000250|UniProtKB:P62805 |
| Chain | Residue | Details |
| B | LYS31 | |
| F | LYS31 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250|UniProtKB:P62805 |
| Chain | Residue | Details |
| A | LYS37 | |
| B | LYS91 | |
| F | LYS91 |
| site_id | SWS_FT_FI14 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:Q71DI3 |
| Chain | Residue | Details |
| A | TYR41 | |
| E | TYR41 |
| site_id | SWS_FT_FI15 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P84228 |
| Chain | Residue | Details |
| A | LYS56 | |
| A | LYS79 | |
| E | LYS56 | |
| E | LYS79 |
| site_id | SWS_FT_FI16 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q71DI3 |
| Chain | Residue | Details |
| A | SER57 | |
| E | SER57 |
| site_id | SWS_FT_FI17 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q71DI3 |
| Chain | Residue | Details |
| A | THR80 | |
| A | THR107 | |
| E | THR80 | |
| E | THR107 |
| site_id | SWS_FT_FI18 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P84243 |
| Chain | Residue | Details |
| A | SER86 | |
| E | SER86 |
| site_id | SWS_FT_FI19 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-glutaryllysine; alternate => ECO:0000250|UniProtKB:Q71DI3 |
| Chain | Residue | Details |
| A | LYS115 | |
| E | LYS115 |
| site_id | SWS_FT_FI20 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q71DI3 |
| Chain | Residue | Details |
| A | LYS122 | |
| E | LYS122 |
| site_id | SWS_FT_FI21 |
| Number of Residues | 2 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000250|UniProtKB:Q71DI3 |
| Chain | Residue | Details |
| A | ALA110 | |
| E | ALA110 |
