5OKZ
Crystal Strucrure of the Mpp6 Exosome complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | m, I, S, c | Exosome complex component CSL4 | polymer | 295 | 31911.6 | 4 | UniProt (P53859) Pfam (PF21551) Pfam (PF10447) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | CEP1 synthetic lethal protein 4 |
2 | A, K, U, e | Exosome complex component RRP45 | polymer | 305 | 34001.9 | 4 | UniProt (Q05636) Pfam (PF01138) Pfam (PF03725) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Ribosomal RNA-processing protein 45 |
3 | B, L, V, f | Exosome complex component SKI6 | polymer | 249 | 27892.0 | 4 | UniProt (P46948) Pfam (PF01138) Pfam (PF03725) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Extracellular mutant protein 20,Ribosomal RNA-processing protein 41,Superkiller protein 6 |
4 | C, M, W, g | Exosome complex component RRP43 | polymer | 394 | 44093.0 | 4 | UniProt (P25359) Pfam (PF01138) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Ribosomal RNA-processing protein 43 |
5 | D, N, X, h | Exosome complex component RRP46 | polymer | 226 | 24659.4 | 4 | UniProt (P53256) Pfam (PF01138) Pfam (PF03725) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Ribosomal RNA-processing protein 46 |
6 | E, O, Y, i | Exosome complex component RRP42 | polymer | 268 | 29391.5 | 4 | UniProt (Q12277) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Ribosomal RNA-processing protein 42 |
7 | F, P, Z, j | Exosome complex component MTR3 | polymer | 250 | 27573.9 | 4 | UniProt (P48240) Pfam (PF01138) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | mRNA transport regulator 3 |
8 | G, Q, a, k | Exosome complex component RRP40 | polymer | 244 | 26939.7 | 4 | UniProt (Q08285) Pfam (PF21262) Pfam (PF15985) Pfam (PF18311) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Ribosomal RNA-processing protein 40 |
9 | H, R, b, l | Exosome complex component RRP4 | polymer | 316 | 34603.1 | 4 | UniProt (P38792) Pfam (PF14382) Pfam (PF21266) Pfam (PF15985) In PDB | Saccharomyces cerevisiae (Baker's yeast) | Ribosomal RNA-processing protein 4 |
10 | J, T, d, n | M-phase phosphoprotein 6 homolog | polymer | 190 | 21541.9 | 4 | UniProt (P53725) Pfam (PF10175) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Exosome-associated RNA-binding protein MPP6 |
11 | A, K, U, e | TRIS(HYDROXYETHYL)AMINOMETHANE | non-polymer | 163.2 | 4 | Chemie (TAM) | |||
12 | l, G, H, R, b... | CHLORIDE ION | non-polymer | 35.5 | 7 | Chemie (CL) | |||
13 | O, g | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
14 | water | water | 18.0 | 140 | Chemie (HOH) |
Sequence modifications
m, I, S, c: 1 - 292 (UniProt: P53859)
B, L, V, f: 1 - 246 (UniProt: P46948)
C, M, W, g: 1 - 394 (UniProt: P25359)
D, N, X, h: 1 - 223 (UniProt: P53256)
E, O, Y, i: 1 - 265 (UniProt: Q12277)
F, P, Z, j: 1 - 250 (UniProt: P48240)
G, Q, a, k: 1 - 240 (UniProt: Q08285)
H, R, b, l: 50 - 359 (UniProt: P38792)
J, T, d, n: 1 - 186 (UniProt: P53725)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Pro -1 | - | expression tag |
His 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Pro -1 | - | expression tag |
His 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 363 | Val 363 | conflict |
PDB | External Database | Details |
---|---|---|
Ala -2 | - | expression tag |
Ala -1 | - | expression tag |
Ser 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Pro -1 | - | expression tag |
His 0 | - | expression tag |
Ile 138 | Val 138 | conflict |
PDB | External Database | Details |
---|---|---|
Thr 161 | Met 161 | conflict |
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Pro -2 | - | expression tag |
Asp -1 | - | expression tag |
Ser 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Thr 44 | - | expression tag |
Gly 45 | - | expression tag |
Gly 46 | - | expression tag |
Arg 47 | - | expression tag |
Ser 48 | - | expression tag |
Met 49 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Pro -2 | - | expression tag |
Asp -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 40 |
Total formula weight | 1210432.2 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 949.6 | |
All* | Total formula weight | 1211381.8 |