5OFA
Crystal structure of human MORC2 (residues 1-603) with spinal muscular atrophy mutation T424R
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | MORC family CW-type zinc finger protein 2 | polymer | 606 | 70075.1 | 2 | UniProt (Q9Y6X9) Pfam (PF13589) Pfam (PF17942) Pfam (PF07496) | Homo sapiens (Human) | Zinc finger CW-type coiled-coil domain protein 1 |
| 2 | C, F (B, A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, G (B, A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 4 | E, H (B, A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | I, J (B, A) | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 603 (UniProt: Q9Y6X9)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Arg 0 | - | expression tag |
| Arg 424 | Thr 424 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 140150.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1191.8 | |
| All* | Total formula weight | 141342.0 |
