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5O33

A structure of the GEF Kalirin DH1 domain in complex with the small GTPase Rac1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Ras-related C3 botulinum toxin substrate 1polymer17719710.81UniProt (P63000)
Pfam (PF00071)
Homo sapiens (Human)Cell migration-inducing gene 5 protein,Ras-like protein TC25,p21-Rac1
2B
(B)
Kalirinpolymer18021056.21UniProt (P97924)
Pfam (PF00621)
Rattus norvegicus (Rat)Huntingtin-associated protein-interacting protein,PAM COOH-terminal interactor protein 10,P-CIP10,Protein Duo,Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain
3C, D, F, G, H...
(A, B)
1,2-ETHANEDIOLnon-polymer62.16Chemie (EDO)
4E
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
5J, K
(A, B)
waterwater18.0282Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight40767.0
Non-Polymers*Number of molecules7
Total formula weight815.6
All*Total formula weight41582.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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