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5O2S

Human KRAS in complex with darpin K27

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G
(A, C, E, G)
GTPase KRaspolymer16919208.64UniProt (P01116)
Pfam (PF00071)
Homo sapiens (Human)K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
2B, D, F, H
(B, D, F, H)
darpin K27polymer17819530.94Homo sapiens (Human)
3I, K, M, O
(A, C, E, G)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.24Chemie (GDP)
4J, L, N, P
(A, C, E, G)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
5Q, R, S, T, U...
(A, B, C, D, E...)
waterwater18.059Chemie (HOH)
Sequence modifications
A, C, E, G: 1 - 166 (UniProt: P01116)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ser -1-expression tag
His 0-expression tag
Val 12Gly 12variant
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight154958.3
Non-Polymers*Number of molecules8
Total formula weight1870.0
All*Total formula weight156828.3
*Water molecules are not included.

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PDB entries from 2025-06-11

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