5O14
Co-crystal structure of a cross-reactive bactericidal human antibody targeting meningococcal vaccine antigen factor H binding protein
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Factor H binding protein variant 1.1 | polymer | 257 | 27699.9 | 2 | UniProt (Q9JXV4) Pfam (PF20937) Pfam (PF08794) In PDB | Neisseria meningitidis serogroup B (strain MC58) | |
2 | C, H | Fab 1A12 Heavy Chain | polymer | 235 | 25461.6 | 2 | Homo sapiens | ||
3 | D, L | Fab 1A12 Light Chain | polymer | 217 | 23670.3 | 2 | Homo sapiens | ||
4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
5 | C, H | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
6 | water | water | 18.0 | 917 | Chemie (HOH) |
Sequence modifications
A, B: 8 - 255 (UniProt: Q9JXV4)
PDB | External Database | Details |
---|---|---|
Met 7 | - | initiating methionine |
Leu 256 | - | expression tag |
Glu 257 | - | expression tag |
His 258 | - | expression tag |
His 259 | - | expression tag |
His 260 | - | expression tag |
His 261 | - | expression tag |
His 262 | - | expression tag |
His 263 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 153663.7 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 257.1 | |
All* | Total formula weight | 153920.8 |