5NVM
Crystal structure of the human 4EHP-GIGYF2 complex lacking the auxiliary sequences
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Eukaryotic translation initiation factor 4E type 2 | polymer | 189 | 21979.1 | 2 | UniProt (O60573) Pfam (PF01652) In PDB | Homo sapiens (Human) | eIF4E type 2,Eukaryotic translation initiation factor 4E homologous protein,Eukaryotic translation initiation factor 4E-like 3,eIF4E-like protein 4E-LP,mRNA cap-binding protein 4EHP,h4EHP,mRNA cap-binding protein type 3 |
2 | B, D | GRB10-interacting GYF protein 2 | polymer | 42 | 5018.9 | 2 | UniProt (Q6Y7W6) In PDB | Homo sapiens (Human) | PERQ amino acid-rich with GYF domain-containing protein 2,Trinucleotide repeat-containing gene 15 protein |
3 | A, B, C, D | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
4 | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A, C: 52 - 234 (UniProt: O60573)
B, D: 35 - 72 (UniProt: Q6Y7W6)
PDB | External Database | Details |
---|---|---|
Gly 46 | - | expression tag |
Pro 47 | - | expression tag |
His 48 | - | expression tag |
Met 49 | - | expression tag |
Leu 50 | - | expression tag |
Glu 51 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 31 | - | expression tag |
Pro 32 | - | expression tag |
His 33 | - | expression tag |
Met 34 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 53996.0 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 379.9 | |
All* | Total formula weight | 54375.9 |