Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003743 | molecular_function | translation initiation factor activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006413 | biological_process | translational initiation |
| C | 0003723 | molecular_function | RNA binding |
| C | 0003743 | molecular_function | translation initiation factor activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006413 | biological_process | translational initiation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | binding site for residue PO4 A 301 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 B 101 |
| Chain | Residue |
| A | ARG96 |
| B | PRO59 |
| B | SER60 |
| B | HOH205 |
| B | HOH208 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 C 301 |
| Chain | Residue |
| C | HOH403 |
| C | ARG103 |
| C | SER145 |
| C | ARG146 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 D 101 |
| Chain | Residue |
| C | ARG96 |
| D | PRO59 |
| D | SER60 |
| D | HOH201 |
| D | HOH207 |
Functional Information from PROSITE/UniProt
| site_id | PS00813 |
| Number of Residues | 24 |
| Details | IF4E Eukaryotic initiation factor 4E signature. DFhlFKegIkPmWEDdanknGGKW |
| Chain | Residue | Details |
| A | ASP112-TRP135 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 28 |
| Details | Region: {"description":"EIF4EBP1/2/3 binding","evidences":[{"source":"PubMed","id":"17368478","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P06730","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17368478","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ISG15); alternate","evidences":[{"source":"PubMed","id":"17289916","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 20 |
| Details | Motif: {"description":"4EHP-binding motif","evidences":[{"source":"PubMed","id":"22751931","evidenceCode":"ECO:0000269"}]} |
