5NVK

Crystal structure of the human 4EHP-GIGYF1 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G	Eukaryotic translation initiation factor 4E type 2	polymer	189	21979.1	4	UniProt (O60573) Pfam (PF01652) In PDB	Homo sapiens (Human)	eIF4E type 2,Eukaryotic translation initiation factor 4E homologous protein,Eukaryotic translation initiation factor 4E-like 3,eIF4E-like protein 4E-LP,mRNA cap-binding protein 4EHP,h4EHP,mRNA cap-binding protein type 3
2	B, D, F, H	GRB10-interacting GYF protein 1	polymer	75	8733.0	4	UniProt (O75420) In PDB	Homo sapiens (Human)	PERQ amino acid-rich with GYF domain-containing protein 1

Sequence modifications

A, C, E, G: 52 - 234 (UniProt: O60573)

PDB	External Database	Details
Gly 46	-	expression tag
Pro 47	-	expression tag
His 48	-	expression tag
Met 49	-	expression tag
Leu 50	-	expression tag
Glu 51	-	expression tag

B, D, F, H: 33 - 103 (UniProt: O75420)

PDB	External Database	Details
Gly 29	-	expression tag
Pro 30	-	expression tag
His 31	-	expression tag
Met 32	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	122848.3
All*	Total formula weight	122848.3

*Water molecules are not included.