5NRW
Crystal structure of the human bromodomain of CREBBP bound to the inhibitor XDM4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | CREB-binding protein | polymer | 119 | 14223.3 | 1 | UniProt (Q92793) Pfam (PF00439) In PDB | Homo sapiens (Human) | |
| 2 | A | 4-ethanoyl-3-ethyl-5-methyl-~{N}-(naphthalen-1-ylmethyl)-1~{H}-pyrrole-2-carboxamide | non-polymer | 334.4 | 1 | Chemie (96N) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence modifications
A: 1081 - 1197 (UniProt: Q92793)
| PDB | External Database | Details |
|---|---|---|
| Ser 1079 | - | expression tag |
| Met 1080 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14223.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 582.7 | |
| All* | Total formula weight | 14806.0 |
