5NLB
Crystal structure of human CUL3 N-terminal domain bound to KEAP1 BTB and 3-box
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Kelch-like ECH-associated protein 1 | polymer | 154 | 17147.7 | 1 | UniProt (Q14145) Pfam (PF00651) In PDB | Homo sapiens (Human) | Cytosolic inhibitor of Nrf2,INrf2,Kelch-like protein 19 |
| 2 | B | Cullin-3 | polymer | 356 | 41747.7 | 1 | UniProt (Q13618) Pfam (PF00888) In PDB | Homo sapiens (Human) | CUL-3 |
Sequence modifications
B: 26 - 381 (UniProt: Q13618)
| PDB | External Database | Details |
|---|---|---|
| Arg 342 | Ile 342 | engineered mutation |
| Asp 346 | Leu 346 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58895.5 | |
| All* | Total formula weight | 58895.5 |
