5NI0

VIM-2_10c. Metallo-beta-Lactamase Inhibitors by Bioisosteric Replacement: Preparation, Activity and Binding

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, E)	Beta-lactamase class B VIM-2	polymer	266	28352.8	2	UniProt (Q9K2N0) Pfam (PF00753)	Pseudomonas aeruginosa	BlaVIM-2,Class B carbapenemase VIM-2,Metallo beta-lactamase,Metallo-beta lactamase protein,Metallo-beta-lactamase VIM-2,VIM-2,VIM-2 beta-lactamase,VIM-2 class B metallo b-lactamase,VIM-2 type metallo-beta-lactamase
2	C, D, F, G (A, E)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	E, H (A, E)	[(2~{R})-1-ethanoylsulfanyl-6-phenyl-hexan-2-yl]phosphonic acid	non-polymer		316.4	2	Chemie (8XW)
4	I, J (A, E)	water	water		18.0	458	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56705.7
Non-Polymers*	Number of molecules	6
	Total formula weight	894.3
All*	Total formula weight	57600.0

*Water molecules are not included.