5N92
Crystal Structure of Human IL-17AF
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interleukin-17A | polymer | 132 | 15146.1 | 1 | UniProt (Q16552) Pfam (PF06083) | Homo sapiens (Human) | IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8 |
| 2 | B (F) | Interleukin-17F | polymer | 139 | 15695.9 | 1 | UniProt (Q96PD4) Pfam (PF06083) | Homo sapiens (Human) | IL-17F,Cytokine ML-1 |
| 3 | C (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 4 | D, E (A, F) | water | water | 18.0 | 96 | Chemie (HOH) |
Sequence modifications
F: 31 - 163 (UniProt: Q96PD4)
| PDB | External Database | Details |
|---|---|---|
| Glu 25 | - | expression tag |
| Phe 26 | - | expression tag |
| Arg 27 | - | expression tag |
| His 28 | - | expression tag |
| Asp 29 | - | expression tag |
| Ser 30 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30842.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 570.5 | |
| All* | Total formula weight | 31412.6 |
