Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5N92

Crystal Structure of Human IL-17AF

Functional Information from GO Data
ChainGOidnamespacecontents
A0002225biological_processpositive regulation of antimicrobial peptide production
A0002250biological_processadaptive immune response
A0002376biological_processimmune system process
A0005125molecular_functioncytokine activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006915biological_processapoptotic process
A0006954biological_processinflammatory response
A0006955biological_processimmune response
A0007219biological_processNotch signaling pathway
A0007267biological_processcell-cell signaling
A0008219biological_processcell death
A0009611biological_processresponse to wounding
A0009897cellular_componentexternal side of plasma membrane
A0010467biological_processgene expression
A0030216biological_processkeratinocyte differentiation
A0032731biological_processpositive regulation of interleukin-1 beta production
A0032735biological_processpositive regulation of interleukin-12 production
A0032739biological_processpositive regulation of interleukin-16 production
A0032747biological_processpositive regulation of interleukin-23 production
A0032755biological_processpositive regulation of interleukin-6 production
A0032760biological_processpositive regulation of tumor necrosis factor production
A0038173biological_processinterleukin-17A-mediated signaling pathway
A0042803molecular_functionprotein homodimerization activity
A0043616biological_processkeratinocyte proliferation
A0045087biological_processinnate immune response
A0045672biological_processpositive regulation of osteoclast differentiation
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0046982molecular_functionprotein heterodimerization activity
A0050829biological_processdefense response to Gram-negative bacterium
A0050830biological_processdefense response to Gram-positive bacterium
A0050832biological_processdefense response to fungus
A0060729biological_processintestinal epithelial structure maintenance
A0071347biological_processcellular response to interleukin-1
A0072537biological_processfibroblast activation
A0097400biological_processinterleukin-17-mediated signaling pathway
A0097530biological_processgranulocyte migration
A0106015biological_processnegative regulation of inflammatory response to wounding
A1900017biological_processpositive regulation of cytokine production involved in inflammatory response
A1903348biological_processpositive regulation of bicellular tight junction assembly
A2000340biological_processpositive regulation of chemokine (C-X-C motif) ligand 1 production
F0001819biological_processpositive regulation of cytokine production
F0002225biological_processpositive regulation of antimicrobial peptide production
F0002250biological_processadaptive immune response
F0002376biological_processimmune system process
F0005125molecular_functioncytokine activity
F0005126molecular_functioncytokine receptor binding
F0005515molecular_functionprotein binding
F0005576cellular_componentextracellular region
F0005615cellular_componentextracellular space
F0006954biological_processinflammatory response
F0016525biological_processnegative regulation of angiogenesis
F0017015biological_processregulation of transforming growth factor beta receptor signaling pathway
F0019955molecular_functioncytokine binding
F0032645biological_processregulation of granulocyte macrophage colony-stimulating factor production
F0032663biological_processregulation of interleukin-2 production
F0032675biological_processregulation of interleukin-6 production
F0032677biological_processregulation of interleukin-8 production
F0032755biological_processpositive regulation of interleukin-6 production
F0032761biological_processpositive regulation of lymphotoxin A production
F0042803molecular_functionprotein homodimerization activity
F0045087biological_processinnate immune response
F0045944biological_processpositive regulation of transcription by RNA polymerase II
F0046982molecular_functionprotein heterodimerization activity
F0050829biological_processdefense response to Gram-negative bacterium
F0050830biological_processdefense response to Gram-positive bacterium
F0051216biological_processcartilage development
F0097400biological_processinterleukin-17-mediated signaling pathway
F1900017biological_processpositive regulation of cytokine production involved in inflammatory response
F2000340biological_processpositive regulation of chemokine (C-X-C motif) ligand 1 production
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19838198
ChainResidueDetails
FASN83

218853

PDB entries from 2024-04-24

PDB statisticsPDBj update infoContact PDBjnumon