5N7Q
CRYSTAL STRUCTURE OF MATURE CATHEPSIN D FROM THE TICK IXODES RICINUS (IRCD1) IN COMPLEX WITH THE INHIBITOR PEPSTATIN A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Putative cathepsin d | polymer | 339 | 36787.2 | 2 | UniProt (V5HCK7) Pfam (PF00026) In PDB | Ixodes ricinus (Common tick) | |
| 2 | I, J | PEPSTATIN A | polymer | 6 | 685.9 | 2 | BIRD (PRD_000557) | Actinobacteria | |
| 3 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 4 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 1308 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 339 (UniProt: V5HCK7)
| PDB | External Database | Details |
|---|---|---|
| Val 17 | Glu 60 | conflict |
| Leu 160 | Arg 203 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 74946.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 198.2 | |
| All* | Total formula weight | 75144.5 |
