Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue PEG A 401 |
| Chain | Residue |
| A | ASN83 |
| A | HOH652 |
| A | HOH659 |
| A | HOH766 |
| A | HOH772 |
| A | HOH796 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 401 |
| Chain | Residue |
| B | HOH523 |
| B | HOH600 |
| B | HOH885 |
| B | HOH948 |
| B | TYR322 |
| B | GLU337 |
| B | HOH507 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide IVA I 501 and VAL I 502 |
| Chain | Residue |
| A | VAL16 |
| A | SER81 |
| A | GLY229 |
| A | THR230 |
| A | SER231 |
| A | LEU232 |
| A | GLN256 |
| A | HOH539 |
| I | VAL503 |
| I | STA504 |
| I | HOH606 |
| I | HOH607 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide VAL I 503 and STA I 504 |
| Chain | Residue |
| A | ILE34 |
| A | ASP36 |
| A | GLY38 |
| A | TYR79 |
| A | GLY80 |
| A | SER81 |
| A | ASP227 |
| A | GLY229 |
| A | THR230 |
| I | IVA501 |
| I | VAL502 |
| I | ALA505 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | binding site for Di-peptide STA I 504 and ALA I 505 |
| Chain | Residue |
| A | ILE34 |
| A | ASP36 |
| A | GLY38 |
| A | SER39 |
| A | VAL78 |
| A | TYR79 |
| A | GLY80 |
| A | TYR196 |
| A | ASP227 |
| A | GLY229 |
| A | THR230 |
| I | VAL502 |
| I | VAL503 |
| I | STA506 |
| I | HOH608 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | binding site for Di-peptide ALA I 505 and STA I 506 |
| Chain | Residue |
| A | GLY38 |
| A | SER39 |
| A | VAL78 |
| A | TYR79 |
| A | GLY80 |
| A | TYR196 |
| I | STA504 |
| I | HOH601 |
| I | HOH602 |
| I | HOH603 |
| I | HOH604 |
| I | HOH605 |
| I | HOH608 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide IVA J 501 and VAL J 502 |
| Chain | Residue |
| B | SER81 |
| B | GLY229 |
| B | THR230 |
| B | SER231 |
| B | GLN256 |
| B | HOH528 |
| B | HOH581 |
| J | VAL503 |
| J | HOH601 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide VAL J 503 and STA J 504 |
| Chain | Residue |
| B | ILE34 |
| B | ASP36 |
| B | GLY38 |
| B | TYR79 |
| B | GLY80 |
| B | SER81 |
| B | ASP227 |
| B | GLY229 |
| B | THR230 |
| J | VAL502 |
| J | ALA505 |
| J | STA506 |
| site_id | AC9 |
| Number of Residues | 14 |
| Details | binding site for Di-peptide STA J 504 and ALA J 505 |
| Chain | Residue |
| J | HOH603 |
| B | ILE34 |
| B | ASP36 |
| B | GLY38 |
| B | SER39 |
| B | VAL78 |
| B | TYR79 |
| B | GLY80 |
| B | TYR196 |
| B | ASP227 |
| B | GLY229 |
| B | THR230 |
| J | VAL503 |
| J | STA506 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide ALA J 505 and STA J 506 |
| Chain | Residue |
| B | GLY38 |
| B | SER39 |
| B | VAL78 |
| B | GLY80 |
| B | TYR196 |
| J | STA504 |
| J | HOH602 |
| J | HOH603 |
| J | HOH604 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. VIFDTGSANLWL |
| Chain | Residue | Details |
| A | VAL33-LEU44 | |
| A | ALA224-GLY235 | |
