5N69
Cardiac muscle myosin S1 fragment in the pre-powerstroke state co-crystallized with the activator Omecamtiv Mecarbil
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Myosin-7 | polymer | 828 | 94834.7 | 2 | UniProt (Q9BE39) Pfam (PF02736) Pfam (PF00063) In PDB | Bos taurus (Bovine) | Myosin heavy chain 7,Myosin heavy chain slow isoform,MyHC-slow,Myosin heavy chain,cardiac muscle beta isoform,MyHC-beta |
| 2 | G, H | Myosin light chain 3 | polymer | 199 | 21968.0 | 2 | UniProt (P85100) In PDB | Bos taurus (Bovine) | Myosin light chain 1,slow-twitch muscle B/ventricular isoform,MLC1SB |
| 3 | A, B | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 4 | A, B | VANADATE ION | non-polymer | 114.9 | 2 | Chemie (VO4) | |||
| 5 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | A, B | methyl 4-(2-fluoro-3-{[(6-methylpyridin-3-yl)carbamoyl]amino}benzyl)piperazine-1-carboxylate | non-polymer | 401.4 | 2 | Chemie (2OW) | |||
| 7 | B, A, H | GLYCEROL | non-polymer | 92.1 | 25 | Chemie (GOL) | |||
| 8 | B | 3,3',3''-phosphanetriyltripropanoic acid | non-polymer | 250.2 | 1 | Chemie (TCE) | |||
| 9 | water | water | 18.0 | 844 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 233605.5 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 4488.3 | |
| All* | Total formula weight | 238093.8 |
