Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003774 | molecular_function | cytoskeletal motor activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0016459 | cellular_component | myosin complex |
| A | 0051015 | molecular_function | actin filament binding |
| B | 0003774 | molecular_function | cytoskeletal motor activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0016459 | cellular_component | myosin complex |
| B | 0051015 | molecular_function | actin filament binding |
| G | 0003774 | molecular_function | cytoskeletal motor activity |
| G | 0005509 | molecular_function | calcium ion binding |
| G | 0016459 | cellular_component | myosin complex |
| G | 0016460 | cellular_component | myosin II complex |
| G | 0031674 | cellular_component | I band |
| G | 0060048 | biological_process | cardiac muscle contraction |
| H | 0003774 | molecular_function | cytoskeletal motor activity |
| H | 0005509 | molecular_function | calcium ion binding |
| H | 0016459 | cellular_component | myosin complex |
| H | 0016460 | cellular_component | myosin II complex |
| H | 0031674 | cellular_component | I band |
| H | 0060048 | biological_process | cardiac muscle contraction |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue ADP A 901 |
| Chain | Residue |
| A | ILE114 |
| A | LYS184 |
| A | THR185 |
| A | VAL186 |
| A | ASN238 |
| A | VO4902 |
| A | MG903 |
| A | HOH1003 |
| A | HOH1030 |
| A | HOH1065 |
| A | HOH1079 |
| A | ASN126 |
| A | PRO127 |
| A | M3L129 |
| A | TRP130 |
| A | TYR134 |
| A | GLY181 |
| A | ALA182 |
| A | GLY183 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue VO4 A 902 |
| Chain | Residue |
| A | SER180 |
| A | GLY181 |
| A | LYS184 |
| A | ASN238 |
| A | SER241 |
| A | SER242 |
| A | GLY464 |
| A | ADP901 |
| A | MG903 |
| A | HOH1020 |
| A | HOH1042 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 903 |
| Chain | Residue |
| A | THR185 |
| A | SER242 |
| A | ADP901 |
| A | VO4902 |
| A | HOH1003 |
| A | HOH1020 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | binding site for residue 2OW A 904 |
| Chain | Residue |
| A | LYS146 |
| A | ARG147 |
| A | ASN160 |
| A | TYR164 |
| A | THR167 |
| A | ASP168 |
| A | HIS492 |
| A | HIS666 |
| A | PRO710 |
| A | ASN711 |
| A | ARG712 |
| A | ILE713 |
| A | TYR722 |
| A | LEU770 |
| A | GLU774 |
| A | HOH1017 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 905 |
| Chain | Residue |
| A | ASN361 |
| A | LYS363 |
| A | ASP376 |
| A | GLU379 |
| A | GLU380 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 906 |
| Chain | Residue |
| A | PHE494 |
| A | GLN498 |
| A | PHE510 |
| A | ILE511 |
| A | ASP512 |
| A | PHE513 |
| A | GLY514 |
| A | MET515 |
| A | HOH1043 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 907 |
| Chain | Residue |
| A | PHE244 |
| A | GLY245 |
| A | TYR266 |
| A | LEU267 |
| A | ALA463 |
| A | CYS477 |
| A | ILE478 |
| A | THR481 |
| A | HIS651 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 908 |
| Chain | Residue |
| A | GLU269 |
| A | SER271 |
| A | ARG272 |
| A | PHE275 |
| A | GLU474 |
| A | GLN475 |
| A | HOH1034 |
| A | HOH1115 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 909 |
| Chain | Residue |
| A | MET6 |
| A | ALA7 |
| A | PHE9 |
| A | ARG17 |
| A | PRO151 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 910 |
| Chain | Residue |
| A | PHE275 |
| A | LEU277 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 911 |
| Chain | Residue |
| A | LEU267 |
| A | LEU268 |
| A | LYS270 |
| A | SER271 |
| A | GLU474 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 912 |
| Chain | Residue |
| A | PHE470 |
| A | LEU277 |
| A | ALA279 |
| A | PHE468 |
| A | ASP469 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 913 |
| Chain | Residue |
| A | GLU537 |
| A | PHE540 |
| A | LYS542 |
| A | ALA543 |
| A | THR547 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 914 |
| Chain | Residue |
| A | TRP130 |
| A | LEU131 |
| site_id | AD6 |
| Number of Residues | 1 |
| Details | binding site for residue GOL A 915 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 916 |
| Chain | Residue |
| A | ARG739 |
| A | HIS760 |
| A | HOH1104 |
| site_id | AD8 |
| Number of Residues | 1 |
| Details | binding site for residue GOL A 917 |
| site_id | AD9 |
| Number of Residues | 19 |
| Details | binding site for residue ADP B 901 |
| Chain | Residue |
| B | ILE114 |
| B | ASN126 |
| B | PRO127 |
| B | M3L129 |
| B | TRP130 |
| B | TYR134 |
| B | GLY181 |
| B | ALA182 |
| B | GLY183 |
| B | LYS184 |
| B | THR185 |
| B | VAL186 |
| B | ASN238 |
| B | VO4902 |
| B | MG903 |
| B | HOH1010 |
| B | HOH1039 |
| B | HOH1080 |
| B | HOH1081 |
| site_id | AE1 |
| Number of Residues | 10 |
| Details | binding site for residue VO4 B 902 |
| Chain | Residue |
| B | SER180 |
| B | GLY181 |
| B | LYS184 |
| B | ASN238 |
| B | SER241 |
| B | SER242 |
| B | GLY464 |
| B | ADP901 |
| B | MG903 |
| B | HOH1009 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 903 |
| Chain | Residue |
| B | THR185 |
| B | SER242 |
| B | ADP901 |
| B | VO4902 |
| B | HOH1001 |
| B | HOH1010 |
| site_id | AE3 |
| Number of Residues | 12 |
| Details | binding site for residue 2OW B 904 |
| Chain | Residue |
| B | LYS146 |
| B | ASN160 |
| B | TYR164 |
| B | THR167 |
| B | ASP168 |
| B | HIS492 |
| B | HIS666 |
| B | PRO710 |
| B | ASN711 |
| B | ARG712 |
| B | TYR722 |
| B | LEU770 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 905 |
| Chain | Residue |
| B | ASP382 |
| B | LEU390 |
| B | ASN391 |
| B | HOH1151 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 906 |
| Chain | Residue |
| B | GLY245 |
| B | TYR266 |
| B | ALA463 |
| B | HIS651 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 907 |
| Chain | Residue |
| B | VAL236 |
| B | LEU277 |
| B | ALA279 |
| B | PHE468 |
| B | ASP469 |
| B | HOH1137 |
| site_id | AE7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 908 |
| Chain | Residue |
| B | PHE494 |
| B | GLN498 |
| B | PHE510 |
| B | ILE511 |
| B | ASP512 |
| B | PHE513 |
| B | MET515 |
| site_id | AE8 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 909 |
| Chain | Residue |
| B | ARG403 |
| B | TYR410 |
| B | ASP607 |
| site_id | AE9 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 910 |
| Chain | Residue |
| A | GLY253 |
| A | ALA254 |
| A | HOH1010 |
| B | GLU536 |
| B | HOH1021 |
| site_id | AF1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 911 |
| Chain | Residue |
| B | GLU269 |
| B | SER271 |
| B | PHE275 |
| B | GLU474 |
| B | GLN475 |
| B | HOH1024 |
| B | HOH1053 |
| B | HOH1112 |
| site_id | AF2 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 912 |
| Chain | Residue |
| B | LYS106 |
| B | ALA110 |
| site_id | AF3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 913 |
| Chain | Residue |
| B | TRP130 |
| B | LEU131 |
| B | PRO132 |
| B | HOH1042 |
| B | HOH1079 |
| site_id | AF4 |
| Number of Residues | 5 |
| Details | binding site for residue TCE B 914 |
| Chain | Residue |
| B | LEU302 |
| B | ASP309 |
| B | GLU379 |
| B | GLU380 |
| B | LYS383 |
| site_id | AF5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL H 201 |
| Chain | Residue |
| H | LEU176 |
| H | ALA178 |
| H | GLY179 |
| H | HIS195 |
| site_id | AF6 |
| Number of Residues | 4 |
| Details | binding site for residue GOL H 202 |
| Chain | Residue |
| A | ARG793 |
| H | GLN93 |
| H | GLU172 |
| H | GOL203 |
| site_id | AF7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL H 203 |
| Chain | Residue |
| H | ARG85 |
| H | GLN93 |
| H | VAL96 |
| H | GOL202 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 98 |
| Details | Domain: {"description":"Myosin N-terminal SH3-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU01190","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 72 |
| Details | Region: {"description":"Actin-binding","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6,N6,N6-trimethyllysine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P02563","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 74 |
| Details | Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 70 |
| Details | Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P16409","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P09542","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P16409","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI11 |
| Number of Residues | 32 |
| Details | Domain: {"description":"EF-hand 3","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI12 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P09542","evidenceCode":"ECO:0000250"}]} |
