5N16
First Bromodomain (BD1) from Candida albicans Bdf1 bound to a dibenzothiazepinone (compound 1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Bromodomain-containing factor 1 | polymer | 138 | 15476.9 | 4 | UniProt (Q5A4W8) Pfam (PF00439) | Candida albicans (Yeast) | |
| 2 | E, H, J, M (A, C, D) | 5-cyclopropyl-2-(5-pyrazin-2-yl-1,2,4-oxadiazol-3-yl)benzo[b][1,4]benzothiazepin-6-one | non-polymer | 413.5 | 4 | Chemie (8FN) | |||
| 3 | F, G, I, L, N (A, B, C, D) | NICKEL (II) ION | non-polymer | 58.7 | 5 | Chemie (NI) | |||
| 4 | K (C) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 648 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 193 - 327 (UniProt: Q5A4W8)
| PDB | External Database | Details |
|---|---|---|
| Ala 190 | - | expression tag |
| Ala 191 | - | expression tag |
| Gly 192 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 61907.7 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2039.4 | |
| All* | Total formula weight | 63947.1 |
