5MYG
Crystal structure of the bromodomain of human BRPF1 in complex with NI-57 chemical probe
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Peregrin | polymer | 116 | 13703.7 | 4 | UniProt (P55201) Pfam (PF00439) In PDB | Homo sapiens (Human) | Bromodomain and PHD finger-containing protein 1,Protein Br140 |
2 | A, B, C, D | 4-cyano-~{N}-(1,3-dimethyl-2-oxidanylidene-quinolin-6-yl)-2-methoxy-benzenesulfonamide | non-polymer | 383.4 | 4 | Chemie (LS8) | |||
3 | water | water | 18.0 | 76 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 626 - 740 (UniProt: P55201)
PDB | External Database | Details |
---|---|---|
Ser 625 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 54814.8 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1533.7 | |
All* | Total formula weight | 56348.5 |