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5MYG

Crystal structure of the bromodomain of human BRPF1 in complex with NI-57 chemical probe

Functional Information from PDB Data
site_idAC1
Number of Residues10
Detailsbinding site for residue LS8 A 801
ChainResidue
AASN651
BARG716
AILE652
APHE653
APRO658
ATYR707
AASN708
APHE714
AHOH908
BASP711

site_idAC2
Number of Residues8
Detailsbinding site for residue LS8 B 801
ChainResidue
BILE652
BPHE653
BVAL657
BPRO658
BGLU661
BTYR707
BASN708
BPHE714

site_idAC3
Number of Residues10
Detailsbinding site for residue LS8 C 801
ChainResidue
CILE652
CPHE653
CPRO658
CGLU661
CVAL662
CTYR707
CASN708
CPHE714
CHOH907
DARG686

site_idAC4
Number of Residues11
Detailsbinding site for residue LS8 D 801
ChainResidue
CILE713
DASN651
DILE652
DVAL657
DPRO658
DGLU661
DVAL662
DTYR707
DASN708
DPHE714
DHOH907

Functional Information from PROSITE/UniProt
site_idPS00633
Number of Residues58
DetailsBROMODOMAIN_1 Bromodomain signature. GniFsepvPlsevp..DYLdhIkkpMdfftMkqnleayr..Ylnfddfeedfnl.IvsNClkY
ChainResidueDetails
AGLY650-TYR707

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PDB entries from 2024-11-06

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