5MY8
Crystal structure of SRPK1 in complex with SPHINX31
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SRSF protein kinase 1,SRSF protein kinase 1 | polymer | 383 | 43600.1 | 1 | UniProt (Q96SB4) Pfam (PF00069) | Homo sapiens (Human) | SFRS protein kinase 1,Serine/arginine-rich protein-specific kinase 1,SR-protein-specific kinase 1,SFRS protein kinase 1,Serine/arginine-rich protein-specific kinase 1,SR-protein-specific kinase 1 |
| 2 | B (A) | CITRIC ACID | non-polymer | 192.1 | 1 | Chemie (CIT) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 5 | E, F, G, H, I... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 20 | Chemie (EDO) | |||
| 6 | Y (A) | SPHINX31 | non-polymer | 507.5 | 1 | Chemie (RXZ) | |||
| 7 | Z (A) | water | water | 18.0 | 396 | Chemie (HOH) |
Sequence modifications
A: 58 - 472 (UniProt: Q96SB4)
A: 474 - 655 (UniProt: Q96SB4)
| PDB | External Database | Details |
|---|---|---|
| Ser 56 | - | expression tag |
| Met 57 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 473 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43600.1 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 2111.2 | |
| All* | Total formula weight | 45711.3 |
