Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue CIT A 701 |
| Chain | Residue |
| A | ARG515 |
| A | HOH829 |
| A | ARG515 |
| A | ARG518 |
| A | ARG518 |
| A | ARG561 |
| A | ARG561 |
| A | GOL702 |
| A | HOH801 |
| A | HOH829 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 702 |
| Chain | Residue |
| A | ASP213 |
| A | ASN500 |
| A | ASP511 |
| A | GLN513 |
| A | ARG518 |
| A | ARG561 |
| A | CIT701 |
| A | HOH801 |
| A | HOH813 |
| A | HOH1071 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 703 |
| Chain | Residue |
| A | TYR549 |
| A | TRP606 |
| A | LYS615 |
| A | TYR616 |
| A | EDO714 |
| A | HOH987 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 704 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 705 |
| Chain | Residue |
| A | LEU648 |
| A | HIS650 |
| A | PRO651 |
| A | ASN654 |
| A | HOH806 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 706 |
| Chain | Residue |
| A | THR205 |
| A | HOH811 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 708 |
| Chain | Residue |
| A | ASP138 |
| A | ASN140 |
| A | ASP201 |
| A | TYR202 |
| A | THR205 |
| A | LYS206 |
| A | HOH847 |
| A | HOH874 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 709 |
| Chain | Residue |
| A | ASN529 |
| A | PRO531 |
| A | GLU639 |
| A | HOH833 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 710 |
| Chain | Residue |
| A | VAL582 |
| A | ALA583 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 711 |
| Chain | Residue |
| A | TYR586 |
| A | HOH842 |
| A | HOH995 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 712 |
| Chain | Residue |
| A | TRP618 |
| A | GLU622 |
| A | HOH868 |
| A | HOH1031 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 713 |
| Chain | Residue |
| A | ASN140 |
| A | GLN198 |
| A | HOH815 |
| A | HOH819 |
| A | HOH823 |
| A | HOH911 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 714 |
| Chain | Residue |
| A | TRP606 |
| A | LYS615 |
| A | DMS703 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 715 |
| Chain | Residue |
| A | ASN157 |
| A | LYS615 |
| A | HOH910 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 716 |
| Chain | Residue |
| A | LEU86 |
| A | HIS170 |
| A | TYR227 |
| A | RXZ724 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 718 |
| Chain | Residue |
| A | ARG208 |
| A | HIS505 |
| A | HOH1048 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 719 |
| Chain | Residue |
| A | LYS640 |
| A | ALA642 |
| A | GLU646 |
| A | EDO722 |
| A | HOH844 |
| A | HOH878 |
| A | HOH959 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 720 |
| Chain | Residue |
| A | HIS554 |
| A | TYR559 |
| A | ASP564 |
| A | HOH861 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 721 |
| Chain | Residue |
| A | GLU510 |
| A | GLU557 |
| A | THR560 |
| A | HOH817 |
| site_id | AE2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 722 |
| Chain | Residue |
| A | ASP628 |
| A | PRO632 |
| A | HIS650 |
| A | EDO719 |
| A | HOH878 |
| A | HOH901 |
| A | HOH934 |
| A | HOH994 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 723 |
| Chain | Residue |
| A | CYS207 |
| A | TRP503 |
| A | HOH1007 |
| A | HOH1027 |
| A | SER130 |
| site_id | AE4 |
| Number of Residues | 21 |
| Details | binding site for residue RXZ A 724 |
| Chain | Residue |
| A | LEU86 |
| A | TRP88 |
| A | GLY89 |
| A | SER92 |
| A | VAL94 |
| A | ALA107 |
| A | LYS109 |
| A | PHE165 |
| A | GLU166 |
| A | VAL167 |
| A | LEU168 |
| A | GLY169 |
| A | HIS170 |
| A | LEU220 |
| A | VAL223 |
| A | TYR227 |
| A | ILE228 |
| A | LEU231 |
| A | ALA496 |
| A | EDO716 |
| A | HOH971 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGWGHFSTVWlSwdiqgkkf..........VAMK |
| Chain | Residue | Details |
| A | LEU86-LYS109 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IiHtDIKpeNILL |
| Chain | Residue | Details |
| A | ILE209-LEU221 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 11 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16209947","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by CK2","evidences":[{"source":"PubMed","id":"12565829","evidenceCode":"ECO:0000269"}]} |
