5MXA
Structure of unbound Interleukin-23
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Interleukin-23 subunit alpha | polymer | 198 | 21865.9 | 1 | UniProt (Q9NPF7) Pfam (PF16649) | Homo sapiens (Human) | IL-23-A,Interleukin-23 subunit p19,IL-23p19 |
| 2 | B (A) | Interleukin-12 subunit beta | polymer | 328 | 37212.9 | 1 | UniProt (P29460) Pfam (PF10420) | Homo sapiens (Human) | IL-12B,Cytotoxic lymphocyte maturation factor 40 kDa subunit,CLMF p40,IL-12 subunit p40,NK cell stimulatory factor chain 2,NKSF2 |
| 3 | C (C) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 4 | D, E (B, A) | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
B: 1 - 189 (UniProt: Q9NPF7)
| PDB | External Database | Details |
|---|---|---|
| Gly 190 | - | expression tag |
| Thr 191 | - | expression tag |
| Lys 192 | - | expression tag |
| His 193 | - | expression tag |
| His 194 | - | expression tag |
| His 195 | - | expression tag |
| His 196 | - | expression tag |
| His 197 | - | expression tag |
| His 198 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59078.8 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 748.7 | |
| All* | Total formula weight | 59827.5 |
