5MPA
26S proteasome in presence of ATP (s2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | a, A | Proteasome subunit alpha type-1 | polymer | 252 | 28033.8 | 2 | UniProt (P21243) Pfam (PF00227) Pfam (PF10584) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit C7-alpha,Multicatalytic endopeptidase complex C7,Proteasome component C7-alpha,Proteasome component Y8,Proteinase YSCE subunit 7,SCL1 suppressor protein |
| 2 | b, B | Proteasome subunit alpha type-2 | polymer | 250 | 27191.8 | 2 | UniProt (P23639) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit Y7,Multicatalytic endopeptidase complex subunit Y7,Proteasome component Y7,Proteinase YSCE subunit 7 |
| 3 | c, C | Proteasome subunit alpha type-3 | polymer | 258 | 28748.2 | 2 | UniProt (P23638) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit Y13,Multicatalytic endopeptidase complex subunit Y13,Proteasome component Y13,Proteinase YSCE subunit 13 |
| 4 | d, D | Proteasome subunit alpha type-4 | polymer | 254 | 28478.1 | 2 | UniProt (P40303) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PRE6,Multicatalytic endopeptidase complex subunit PRE6,Proteasome component PRE6,Proteinase YSCE subunit PRE6 |
| 5 | e, E | Proteasome subunit alpha type-5 | polymer | 260 | 28649.1 | 2 | UniProt (P32379) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PUP2,Multicatalytic endopeptidase complex subunit PUP2,Proteasome component PUP2,Proteinase YSCE subunit PUP2 |
| 6 | f, F | Proteasome subunit alpha type-6 | polymer | 234 | 25634.0 | 2 | UniProt (P40302) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PRE5,Multicatalytic endopeptidase complex subunit PRE5,Proteasome component PRE5,Proteinase YSCE subunit PRE5 |
| 7 | g, G | Probable proteasome subunit alpha type-7 | polymer | 288 | 31575.1 | 2 | UniProt (P21242) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit C1,Multicatalytic endopeptidase complex subunit C1,Proteasome component C1,Proteinase YSCE subunit 1 |
| 8 | h, 1 | Proteasome subunit beta type-1 | polymer | 215 | 23573.6 | 2 | UniProt (P38624) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PRE3,Multicatalytic endopeptidase complex subunit PRE3,Proteasome component PRE3,Proteinase YSCE subunit PRE3 |
| 9 | i, 2 | Proteasome subunit beta type-2 | polymer | 261 | 28299.9 | 2 | UniProt (P25043) Pfam (PF00227) Pfam (PF12465) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PUP1,Multicatalytic endopeptidase complex subunit PUP1,Proteasome component PUP1,Proteinase YSCE subunit PUP1 |
| 10 | j, 3 | Proteasome subunit beta type-3 | polymer | 205 | 22627.8 | 2 | UniProt (P25451) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PUP3,Multicatalytic endopeptidase complex subunit PUP3,Proteasome component PUP3 |
| 11 | k, 4 | Proteasome subunit beta type-4 | polymer | 198 | 22545.7 | 2 | UniProt (P22141) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit C11,Multicatalytic endopeptidase complex subunit C11,Proteasome component C11,Proteinase YSCE subunit 11 |
| 12 | l, 5 | Proteasome subunit beta type-5 | polymer | 287 | 31670.5 | 2 | UniProt (P30656) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PRE2,Multicatalytic endopeptidase complex subunit PRE2,Proteasome component PRE2,Proteinase YSCE subunit PRE2 |
| 13 | m, 6 | Proteasome subunit beta type-6 | polymer | 241 | 26905.1 | 2 | UniProt (P23724) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Multicatalytic endopeptidase complex subunit C5,Proteasome component C5 |
| 14 | n, 7 | Proteasome subunit beta type-7 | polymer | 266 | 29471.3 | 2 | UniProt (P30657) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PRE4,Multicatalytic endopeptidase complex subunit PRE4,Proteasome component PRE4,Proteinase YSCE subunit PRE4 |
| 15 | H | 26S protease regulatory subunit 7 homolog | polymer | 467 | 52054.9 | 1 | UniProt (P33299) Pfam (PF21236) Pfam (PF00004) Pfam (PF17862) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Protein CIM5,Tat-binding homolog 3 |
| 16 | I | 26S protease regulatory subunit 4 homolog | polymer | 437 | 48898.2 | 1 | UniProt (P40327) Pfam (PF16450) Pfam (PF00004) Pfam (PF17862) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Tat-binding homolog 5 |
| 17 | K | 26S protease regulatory subunit 6B homolog | polymer | 428 | 47953.7 | 1 | UniProt (P33298) Pfam (PF16450) Pfam (PF00004) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Protein YNT1,Tat-binding homolog 2 |
| 18 | L | 26S protease subunit RPT4 | polymer | 437 | 49480.1 | 1 | UniProt (P53549) Pfam (PF16450) Pfam (PF00004) Pfam (PF17862) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | 26S protease subunit SUG2,Proteasomal cap subunit |
| 19 | M | 26S protease regulatory subunit 6A | polymer | 434 | 48315.7 | 1 | UniProt (P33297) Pfam (PF16450) Pfam (PF00004) Pfam (PF17862) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Tat-binding protein homolog 1,TBP-1 |
| 20 | J | 26S protease regulatory subunit 8 homolog | polymer | 405 | 45342.7 | 1 | UniProt (Q01939) Pfam (PF16450) Pfam (PF00004) Pfam (PF17862) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Protein CIM3,Protein SUG1,Tat-binding protein TBY1 |
| 21 | H, I, K, L, M... | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 22 | H, I, K, L, M | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 5 | Chemie (ATP) | |||
| 23 | J | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 34 |
| Total formula weight | 1058853.5 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3108.9 | |
| All* | Total formula weight | 1061962.4 |
