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5MPA

26S proteasome in presence of ATP (s2)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, O
(a, A)
Proteasome subunit alpha type-1polymer25228033.82UniProt (P21243)
Pfam (PF00227)
Pfam (PF10584)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit C7-alpha,Multicatalytic endopeptidase complex C7,Proteasome component C7-alpha,Proteasome component Y8,Proteinase YSCE subunit 7,SCL1 suppressor protein
2B, P
(b, B)
Proteasome subunit alpha type-2polymer25027191.82UniProt (P23639)
Pfam (PF10584)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit Y7,Multicatalytic endopeptidase complex subunit Y7,Proteasome component Y7,Proteinase YSCE subunit 7
3C, Q
(c, C)
Proteasome subunit alpha type-3polymer25828748.22UniProt (P23638)
Pfam (PF10584)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit Y13,Multicatalytic endopeptidase complex subunit Y13,Proteasome component Y13,Proteinase YSCE subunit 13
4D, R
(d, D)
Proteasome subunit alpha type-4polymer25428478.12UniProt (P40303)
Pfam (PF10584)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PRE6,Multicatalytic endopeptidase complex subunit PRE6,Proteasome component PRE6,Proteinase YSCE subunit PRE6
5E, S
(e, E)
Proteasome subunit alpha type-5polymer26028649.12UniProt (P32379)
Pfam (PF10584)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PUP2,Multicatalytic endopeptidase complex subunit PUP2,Proteasome component PUP2,Proteinase YSCE subunit PUP2
6F, T
(f, F)
Proteasome subunit alpha type-6polymer23425634.02UniProt (P40302)
Pfam (PF10584)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PRE5,Multicatalytic endopeptidase complex subunit PRE5,Proteasome component PRE5,Proteinase YSCE subunit PRE5
7G, U
(g, G)
Probable proteasome subunit alpha type-7polymer28831575.12UniProt (P21242)
Pfam (PF10584)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit C1,Multicatalytic endopeptidase complex subunit C1,Proteasome component C1,Proteinase YSCE subunit 1
8H, V
(h, 1)
Proteasome subunit beta type-1polymer21523573.62UniProt (P38624)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PRE3,Multicatalytic endopeptidase complex subunit PRE3,Proteasome component PRE3,Proteinase YSCE subunit PRE3
9I, W
(i, 2)
Proteasome subunit beta type-2polymer26128299.92UniProt (P25043)
Pfam (PF00227)
Pfam (PF12465)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PUP1,Multicatalytic endopeptidase complex subunit PUP1,Proteasome component PUP1,Proteinase YSCE subunit PUP1
10J, X
(j, 3)
Proteasome subunit beta type-3polymer20522627.82UniProt (P25451)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PUP3,Multicatalytic endopeptidase complex subunit PUP3,Proteasome component PUP3
11K, Y
(k, 4)
Proteasome subunit beta type-4polymer19822545.72UniProt (P22141)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit C11,Multicatalytic endopeptidase complex subunit C11,Proteasome component C11,Proteinase YSCE subunit 11
12L, Z
(l, 5)
Proteasome subunit beta type-5polymer28731670.52UniProt (P30656)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PRE2,Multicatalytic endopeptidase complex subunit PRE2,Proteasome component PRE2,Proteinase YSCE subunit PRE2
13AA, M
(m, 6)
Proteasome subunit beta type-6polymer24126905.12UniProt (P23724)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Multicatalytic endopeptidase complex subunit C5,Proteasome component C5
14BA, N
(n, 7)
Proteasome subunit beta type-7polymer26629471.32UniProt (P30657)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PRE4,Multicatalytic endopeptidase complex subunit PRE4,Proteasome component PRE4,Proteinase YSCE subunit PRE4
15CA
(H)
26S protease regulatory subunit 7 homologpolymer46752054.91UniProt (P33299)
Pfam (PF21236)
Pfam (PF00004)
Pfam (PF17862)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Protein CIM5,Tat-binding homolog 3
16DA
(I)
26S protease regulatory subunit 4 homologpolymer43748898.21UniProt (P40327)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Tat-binding homolog 5
17EA
(K)
26S protease regulatory subunit 6B homologpolymer42847953.71UniProt (P33298)
Pfam (PF16450)
Pfam (PF00004)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Protein YNT1,Tat-binding homolog 2
18FA
(L)
26S protease subunit RPT4polymer43749480.11UniProt (P53549)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)26S protease subunit SUG2,Proteasomal cap subunit
19GA
(M)
26S protease regulatory subunit 6Apolymer43448315.71UniProt (P33297)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Tat-binding protein homolog 1,TBP-1
20HA
(J)
26S protease regulatory subunit 8 homologpolymer40545342.71UniProt (Q01939)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Protein CIM3,Protein SUG1,Tat-binding protein TBY1
21IA, LA, NA, PA, RA...
(H, I, K, L, M...)
MAGNESIUM IONnon-polymer24.36Chemie (MG)
22JA, KA, MA, OA, QA
(H, I, K, L, M)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.25Chemie (ATP)
23SA
(J)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains34
Total formula weight1058853.5
Non-Polymers*Number of molecules12
Total formula weight3108.9
All*Total formula weight1061962.4
*Water molecules are not included.

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PDB entries from 2025-06-11

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