5MO9
Structure of human TrkB receptor ligand binding domain in complex with the Fab frgment of antibody AB20
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | AB20 Fab heavy chain | polymer | 223 | 23675.5 | 1 | Mus musculus (House mouse) | ||
| 2 | B (L) | AB20 Fab light chain | polymer | 219 | 23931.6 | 1 | Mus musculus (House mouse) | ||
| 3 | C (X) | BDNF/NT-3 growth factors receptor | polymer | 151 | 16909.6 | 1 | UniProt (Q16620) Pfam (PF07679) | Homo sapiens (Human) | GP145-TrkB,Trk-B,Neurotrophic tyrosine kinase receptor type 2,TrkB tyrosine kinase,Tropomyosin-related kinase B |
| 4 | D, E, F (H, L, X) | water | water | 18.0 | 169 | Chemie (HOH) |
Sequence modifications
X: 278 - 426 (UniProt: Q16620)
| PDB | External Database | Details |
|---|---|---|
| Met 276 | - | initiating methionine |
| Gly 277 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 64516.7 | |
| All* | Total formula weight | 64516.7 |
