5MLE
Crystal Structure of Human Dihydropyrimidinease-like 2 (DPYSL2A)/Collapsin Response Mediator Protein (CRMP2 13-516) Mutant Y479E/Y499E
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (C, A) | Dihydropyrimidinase-related protein 2 | polymer | 504 | 55036.0 | 2 | UniProt (Q16555) Pfam (PF01979) | Homo sapiens (Human) | DRP-2,Collapsin response mediator protein 2,CRMP-2,N2A3,Unc-33-like phosphoprotein 2,ULIP-2 |
| 2 | C, K, L (C, A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 3 | D, E, F, G, H... (C, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 10 | Chemie (EDO) | |||
| 4 | J, Q (C, A) | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
| 5 | R, S (C, A) | water | water | 18.0 | 175 | Chemie (HOH) |
Sequence modifications
C, A: 13 - 516 (UniProt: Q16555)
| PDB | External Database | Details |
|---|---|---|
| Glu 479 | Tyr 479 | engineered mutation |
| Glu 499 | Tyr 499 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 110072.1 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1056.4 | |
| All* | Total formula weight | 111128.5 |
