5MLB
Crystal structure of human RAS in complex with darpin K27
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | GTPase KRas | polymer | 169 | 19208.6 | 4 | UniProt (P01116) Pfam (PF00071) | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | B, D, F, H (B, D, F, H) | DARPin K27 | polymer | 178 | 19530.9 | 4 | synthetic construct | ||
| 3 | I, K, M, O (A, C, E, G) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 4 | Chemie (GDP) | |||
| 4 | J, L, N, P (A, C, E, G) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 5 | Q, R, S, T, U... (A, B, C, D, E...) | water | water | 18.0 | 59 | Chemie (HOH) |
Sequence modifications
A, C, E, G: 1 - 166 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Val 12 | Gly 12 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 154958.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1870.0 | |
| All* | Total formula weight | 156828.3 |
