5MHJ
ICP4 DNA-binding domain, lacking intrinsically disordered region, in complex with 12mer DNA duplex from its own promoter
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Major viral transcription factor ICP4 | polymer | 201 | 21311.9 | 2 | UniProt (P08392) Pfam (PF03584) | Human herpesvirus 1 (strain 17) (HHV-1) | Alpha-4 protein,Infected cell protein 4,Transcriptional activator IE175 |
| 2 | C (E) | DNA (5'-D(P*CP*GP*AP*TP*CP*GP*TP*CP*C)-3') | polymer | 12 | 3583.3 | 1 | Human herpesvirus 1 | ||
| 3 | D (F) | DNA (5'-D(P*CP*GP*AP*TP*CP*GP*TP*CP*C)-3') | polymer | 12 | 3743.4 | 1 | Human herpesvirus 1 | ||
| 4 | E, G (A, B) | ACETIC ACID | non-polymer | 60.1 | 2 | Chemie (ACY) | |||
| 5 | F (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | H, I, J, K (A, B, E, F) | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence modifications
A, B: 288 - 487 (UniProt: P08392)
| PDB | External Database | Details |
|---|---|---|
| Gly 287 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 49950.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 155.6 | |
| All* | Total formula weight | 50106.2 |
