5MHJ

ICP4 DNA-binding domain, lacking intrinsically disordered region, in complex with 12mer DNA duplex from its own promoter

Summary for 5MHJ

• Entry DOI: 10.2210/pdb5mhj/pdb
• Descriptor: Major viral transcription factor ICP4, DNA (5'-D(P*CP*GP*AP*TP*CP*GP*TP*CP*C)-3'), ACETIC ACID, ... (6 entities in total)
• Functional Keywords: transcription factor, dimer, herpes, virus, transcription
• Biological source: Human herpesvirus 1 (strain 17) (HHV-1); More
• Total number of polymer chains: 4
• Total formula weight: 50106.23

Authors

Tunnicliffe, R.B.,Lockhart-Cairns, M.P.,Levy, C.,Mould, P.,Jowitt, T.A.,Sito, H.,Baldock, C.,Sandri-Goldin, R.M.,Golovanov, A.P. (deposition date: 2016-11-24, release date: 2017-05-24, Last modification date: 2019-04-10)

• Primary citation: Tunnicliffe, R.B.,Lockhart-Cairns, M.P.,Levy, C.,Mould, A.P.,Jowitt, T.A.,Sito, H.,Baldock, C.,Sandri-Goldin, R.M.,Golovanov, A.P.; The herpes viral transcription factor ICP4 forms a novel DNA recognition complex.; Nucleic Acids Res., 45:8064-8078, 2017; PubMed: 28505309; DOI: 10.1093/nar/gkx419

Experimental method

X-RAY DIFFRACTION (2.117 Å)