5MF4
Tubulin-Dictyostatin complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Tubulin alpha-1B chain | polymer | 451 | 50204.4 | 2 | UniProt (P81947) Pfam (PF00091) Pfam (PF03953) | Bos taurus (Cattle) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 2 | B, D (B, D) | Tubulin beta-2B chain | polymer | 445 | 49999.9 | 2 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) | Bos taurus (Cattle) | |
| 3 | E (E) | Stathmin-4 | polymer | 143 | 16844.2 | 1 | UniProt (P63043) Pfam (PF00836) | Rattus norvegicus (Norway Rat) | Stathmin-like protein B3,RB3 |
| 4 | F (F) | Uncharacterized protein | polymer | 384 | 44378.5 | 1 | UniProt (E1BQ43) | Gallus gallus (Chicken) | |
| 5 | G, P (A, C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 6 | H, M, Q, T (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 7 | I, R, W (A, C, F) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 8 | J, K (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 9 | L, S (B, D) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 10 | N, U (B, D) | (3~{Z},5~{E},7~{R},8~{S},10~{S},11~{Z},13~{S},14~{R},15~{S},17~{S},20~{R},21~{S},22~{S})-22-[(2~{S},3~{Z})-hexa-3,5-dien-2-yl]-7,13,15,17,21-pentamethyl-8,10,14,20-tetrakis(oxidanyl)-1-oxacyclodocosa-3,5,11-trien-2-one | non-polymer | 532.8 | 2 | Chemie (7LZ) | |||
| 11 | O, V (B, D) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
| 12 | X (F) | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | non-polymer | 505.2 | 1 | Chemie (ACP) | |||
| 13 | AA, BA, CA, DA, Y... (C, D, E, F, A...) | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence modifications
E: 3 - 145 (UniProt: P63043)
F: 1 - 378 (UniProt: E1BQ43)
| PDB | External Database | Details |
|---|---|---|
| Met 3 | Ile 74 | cloning artifact |
| Ala 4 | Ser 75 | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| His 379 | - | expression tag |
| His 380 | - | expression tag |
| His 381 | - | expression tag |
| His 382 | - | expression tag |
| His 383 | - | expression tag |
| His 384 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 261631.3 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 4295.6 | |
| All* | Total formula weight | 265926.9 |
