5M80

Translation initiation factor 4E in complex with (RP)-iPr-m7GppSpG mRNA 5' cap analog

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, C, B, D)	Eukaryotic translation initiation factor 4E	polymer	190	22145.1	4	UniProt (P63073) Pfam (PF01652)	Mus musculus (House mouse)	mRNA cap-binding protein,eIF-4F 25 kDa subunit
2	E, G (A, B)	[[[(3~{a}~{R},4~{R},6~{R},6~{a}~{R})-4-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-2,2-dimethyl-3~{a},4,6,6~{a}-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methoxy-oxidanyl-phosphoryl]oxy-sulfanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate	non-polymer		859.6	2	Chemie (7L2)
3	F, H (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	I, J, K, L (A, C, B, D)	water	water		18.0	321	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	88580.5
Non-Polymers*	Number of molecules	4
	Total formula weight	1903.3
All*	Total formula weight	90483.8

*Water molecules are not included.