5M2V
Structure of GluK1 ligand-binding domain (S1S2) in complex with (2S,4R)-4-(2-carboxyphenoxy)pyrrolidine-2-carboxylic acid at 3.18 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutamate receptor ionotropic, kainate 1,Glutamate receptor ionotropic, kainate 1 | polymer | 257 | 29108.5 | 2 | UniProt (P22756) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway Rat) | GluK1,Glutamate receptor 5,GluR5,GluK1,Glutamate receptor 5,GluR5 |
| 2 | C, H (A, B) | (2~{S},4~{R})-4-(2-carboxyphenoxy)pyrrolidine-2-carboxylic acid | non-polymer | 251.2 | 2 | Chemie (7E5) | |||
| 3 | D, E, F, I, J... (A, B) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 4 | G, L (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) |
Sequence modifications
A, B: 2 - 116 (UniProt: P22756)
A, B: 119 - 257 (UniProt: P22756)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| Gly 34 | Ala 462 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly 117 | - | linker |
| Thr 118 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58216.9 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1149.8 | |
| All* | Total formula weight | 59366.7 |
