5M2V
Structure of GluK1 ligand-binding domain (S1S2) in complex with (2S,4R)-4-(2-carboxyphenoxy)pyrrolidine-2-carboxylic acid at 3.18 A resolution
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue 7E5 A 301 |
| Chain | Residue |
| A | TYR61 |
| A | GLU190 |
| A | SER193 |
| A | PRO88 |
| A | LEU89 |
| A | THR90 |
| A | ARG95 |
| A | SER141 |
| A | THR142 |
| A | SER173 |
| A | MET189 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | HIS244 |
| A | LYS247 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | ARG31 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | SER22 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 305 |
| Chain | Residue |
| A | GLN238 |
| B | SER213 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | binding site for residue 7E5 B 301 |
| Chain | Residue |
| B | GLU13 |
| B | TYR61 |
| B | PRO88 |
| B | LEU89 |
| B | THR90 |
| B | ARG95 |
| B | SER141 |
| B | THR142 |
| B | MET189 |
| B | GLU190 |
| B | SER193 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 302 |
| Chain | Residue |
| B | HIS244 |
| B | LYS247 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 303 |
| Chain | Residue |
| A | GLU133 |
| B | ARG31 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 B 304 |
| Chain | Residue |
| B | ARG227 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 305 |
| Chain | Residue |
| B | GLN238 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15710405","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YCJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15710405","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15721240","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YCJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine; by PKC","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine; by PKC","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
