5LZI
Porcine heat-labile enterotoxin R13H in complex with inhibitor MM146
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Heat-labile enterotoxin B chain | polymer | 103 | 11788.5 | 5 | UniProt (P32890) Pfam (PF01376) | Escherichia coli | LT-B,porcine,LTP-B |
| 2 | F, I, J, L, O (A, B, C, D) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 3 | G (A) | (2~{R},4~{S},5~{R},6~{R})-5-acetamido-2-[4-[(2~{R})-3-[2-[(2~{S},3~{R},4~{R},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]ethylamino]-3-oxidanylidene-2-(2-phenylethanoylamino)propyl]-1,2,3-triazol-1-yl]-4-oxidanyl-6-[(1~{R},2~{R})-1,2,3-tris(oxidanyl)propyl]oxane-2-carboxylic acid | non-polymer | 754.7 | 1 | Chemie (7BQ) | |||
| 4 | H (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | K, M, P, Q (B, C, D, E) | (2~{R},4~{S},5~{R},6~{R})-5-acetamido-2-[4-[(2~{S})-3-[2-[(2~{S},3~{R},4~{R},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]ethylamino]-3-oxidanylidene-2-(2-phenylethanoylamino)propyl]-1,2,3-triazol-1-yl]-4-oxidanyl-6-[(1~{R},2~{R})-1,2,3-tris(oxidanyl)propyl]oxane-2-carboxylic acid | non-polymer | 754.7 | 4 | Chemie (7DB) | |||
| 6 | N (C) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 7 | R, S, T, U, V (A, B, C, D, E) | water | water | 18.0 | 810 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 103 (UniProt: P32890)
| PDB | External Database | Details |
|---|---|---|
| His 13 | Arg 34 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 58942.5 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 4435.3 | |
| All* | Total formula weight | 63377.7 |
