5LZI

Porcine heat-labile enterotoxin R13H in complex with inhibitor MM146

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0031640	biological_process	killing of cells of another organism
A	0035821	biological_process	modulation of process of another organism
A	0090729	molecular_function	toxin activity
B	0005576	cellular_component	extracellular region
B	0031640	biological_process	killing of cells of another organism
B	0035821	biological_process	modulation of process of another organism
B	0090729	molecular_function	toxin activity
C	0005576	cellular_component	extracellular region
C	0031640	biological_process	killing of cells of another organism
C	0035821	biological_process	modulation of process of another organism
C	0090729	molecular_function	toxin activity
D	0005576	cellular_component	extracellular region
D	0031640	biological_process	killing of cells of another organism
D	0035821	biological_process	modulation of process of another organism
D	0090729	molecular_function	toxin activity
E	0005576	cellular_component	extracellular region
E	0031640	biological_process	killing of cells of another organism
E	0035821	biological_process	modulation of process of another organism
E	0090729	molecular_function	toxin activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue GOL A 201

Chain	Residue
A	ALA1
A	HOH364
A	HOH415
B	ARG35

---

site_id	AC2
Number of Residues	26
Details	binding site for residue 7BQ A 202

Chain	Residue
A	HIS57
A	ILE58
A	GLN61
A	TRP88
A	ASN90
A	LYS91
A	PEG203
A	HOH304
A	HOH306
A	HOH311
A	HOH321
A	HOH324
A	HOH330
A	HOH344
A	HOH355
A	HOH358
A	HOH396
A	HOH420
B	GLY33
B	LYS34
B	HOH361
A	GLU11
A	TYR12
A	HIS13
A	GLU51
A	GLN56

---

site_id	AC3
Number of Residues	2
Details	binding site for residue PEG A 203

Chain	Residue
A	7BQ202
A	HOH358

---

site_id	AC4
Number of Residues	7
Details	binding site for residue GOL B 201

Chain	Residue
A	HOH314
B	TYR18
B	GLU46
B	THR47
B	PRO93
B	ASN94
B	HOH382

---

site_id	AC5
Number of Residues	6
Details	binding site for residue GOL B 202

Chain	Residue
B	THR4
B	ILE5
B	THR6
B	LYS84
B	HOH301
B	HOH309

---

site_id	AC6
Number of Residues	26
Details	binding site for residue 7DB B 203

Chain	Residue
B	GLU51
B	GLN56
B	HIS57
B	GLN61
B	TRP88
B	ASN90
B	LYS91
B	HOH303
B	HOH304
B	HOH332
B	HOH337
B	HOH369
B	HOH374
B	HOH375
B	HOH384
B	HOH408
C	GLU11
C	TYR12
C	HIS13
C	7DB202
C	HOH313
C	HOH320
C	HOH323
C	HOH355
C	HOH379
D	LYS34

---

site_id	AC7
Number of Residues	11
Details	binding site for residue GOL C 201

Chain	Residue
B	HOH346
C	TYR18
C	GLU46
C	THR47
C	PRO93
C	ASN94
C	HOH303
C	HOH393
E	THR15
E	GLN16
E	ASN89

---

site_id	AC8
Number of Residues	29
Details	binding site for residue 7DB C 202

Chain	Residue
C	TRP88
C	ASN90
C	LYS91
C	HOH310
C	HOH313
C	HOH314
C	HOH320
C	HOH322
C	HOH323
C	HOH324
C	HOH372
C	HOH379
B	GLU11
B	TYR12
B	HIS13
B	ASN14
B	7DB203
B	HOH304
B	HOH345
B	HOH369
B	HOH375
B	HOH426
C	GLY33
C	ARG35
C	GLU51
C	SER55
C	GLN56
C	HIS57
C	GLN61

---

site_id	AC9
Number of Residues	8
Details	binding site for residue PO4 C 203

Chain	Residue
C	HIS13
C	ASN14
C	HOH311
C	HOH333
C	HOH398
C	HOH409
E	LYS84
E	HOH319

---

site_id	AD1
Number of Residues	7
Details	binding site for residue GOL D 201

Chain	Residue
D	ILE58
D	ASP59
D	LYS102
D	HOH301
D	HOH397
D	HOH422
E	LYS34

---

site_id	AD2
Number of Residues	27
Details	binding site for residue 7DB D 202

Chain	Residue
A	THR4
A	GLU7
A	HOH325
D	GLU11
D	TYR12
D	HIS13
D	GLU51
D	SER55
D	GLN56
D	GLN61
D	TRP88
D	ASN90
D	LYS91
D	HOH305
D	HOH312
D	HOH319
D	HOH325
D	HOH329
D	HOH334
D	HOH343
D	HOH359
D	HOH363
D	HOH375
D	HOH390
D	HOH398
E	GLY33
E	LYS34

---

site_id	AD3
Number of Residues	27
Details	binding site for residue 7DB E 201

Chain	Residue
A	GLY33
A	LYS34
D	SER44
D	GLY45
D	GLU46
E	GLU11
E	TYR12
E	HIS13
E	GLU51
E	GLN56
E	HIS57
E	GLN61
E	TRP88
E	ASN90
E	LYS91
E	HOH305
E	HOH310
E	HOH313
E	HOH322
E	HOH325
E	HOH343
E	HOH370
E	HOH379
E	HOH380
E	HOH390
E	HOH393
E	HOH410

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