5LRW

Structure of Cezanne/OTUD7B OTU domain bound to ubiquitin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	OTU domain-containing protein 7B	polymer	296	34037.9	2	UniProt (Q6GQQ9) Pfam (PF02338)	Homo sapiens (Human)	Cellular zinc finger anti-NF-kappa-B protein,Zinc finger A20 domain-containing protein 1,Zinc finger protein Cezanne
2	B, D (B, D)	Polyubiquitin-B	polymer	76	8546.8	2	UniProt (P0CG47) Pfam (PF00240)	Homo sapiens (Human)
3	E, F (A, C)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	G, H, I, J (A, B, C, D)	water	water		18.0	621	Chemie (HOH)

Sequence modifications

A, C: 128 - 438 (UniProt: Q6GQQ9)

PDB	External Database	Details
Met 128	Leu 128	cloning artifact
-	Ser 267	deletion
-	Glu 268	deletion
-	Pro 269	deletion
-	Arg 270	deletion
-	Met 271	deletion
-	His 272	deletion
-	Leu 273	deletion
-	Gly 274	deletion
-	Thr 275	deletion
-	Asn 276	deletion
-	Gly 277	deletion
-	Ala 278	deletion
-	Asn 279	deletion
-	Cys 280	deletion
-	Gly 281	deletion
-	Gly 282	deletion
-	Val 283	deletion
-	Glu 284	deletion
-	Ser 285	deletion
-	Ser 286	deletion
-	Glu 287	deletion
-	Glu 288	deletion
Gln 289	Pro 289	linker
Pro 290	Val 290	linker
Gly 291	Tyr 291	linker
Lys 439	-	expression tag
His 440	-	expression tag
His 441	-	expression tag
His 442	-	expression tag
His 443	-	expression tag
His 444	-	expression tag
His 445	-	expression tag

B, D: 1 - 75 (UniProt: P0CG47)

PDB	External Database	Details
Neh 76	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	85169.5
Non-Polymers*	Number of molecules	2
	Total formula weight	184.2
All*	Total formula weight	85353.7

*Water molecules are not included.