5LOW

Structure of the Ca2+-bound Rabphilin 3A C2B domain SNAP25 complex (P21 space group)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, H, I...	Rabphilin-3A	polymer	162	18579.3	6	UniProt (P47709) Pfam (PF00168) In PDB	Rattus norvegicus (Norway Rat)	Exophilin-1
2	D, F, K, M	Synaptosomal-associated protein 25	polymer	95	10841.1	4	UniProt (P60881) In PDB	Rattus norvegicus (Norway Rat)	SNAP-25,Super protein,SUP,Synaptosomal-associated 25 kDa protein
3	E, G, L, N	Synaptosomal-associated protein 25	polymer	82	9223.3	4	UniProt (P60881) In PDB	Rattus norvegicus (Norway Rat)	SNAP-25,Super protein,SUP,Synaptosomal-associated 25 kDa protein
4	K, M, N, A, B...	GLYCEROL	non-polymer		92.1	7	Chemie (GOL)
5	I, J, A, B, C...	CALCIUM ION	non-polymer		40.1	12	Chemie (CA)
6		water	water		18.0	94	Chemie (HOH)

Sequence modifications

A, B, C, H, I, J: 536 - 680 (UniProt: P47709)

PDB	External Database	Details
His 519	-	expression tag
Met 520	-	expression tag
Ala 521	-	expression tag
Ser 522	-	expression tag
Met 523	-	expression tag
Thr 524	-	expression tag
Gly 525	-	expression tag
Gly 526	-	expression tag
Gln 527	-	expression tag
Gln 528	-	expression tag
Met 529	-	expression tag
Gly 530	-	expression tag
Arg 531	-	expression tag
Gly 532	-	expression tag
Ser 533	-	expression tag
Asp 534	-	expression tag
Phe 535	-	expression tag

D, F, K, M: 7 - 82 (UniProt: P60881)

PDB	External Database	Details
Gly -12	-	expression tag
Ser -11	-	expression tag
His -10	-	expression tag
Met -9	-	expression tag
Ala -8	-	expression tag
Ser -7	-	expression tag
Met -6	-	expression tag
Thr -5	-	expression tag
Gly -4	-	expression tag
Gly -3	-	expression tag
Gln -2	-	expression tag
Gln -1	-	expression tag
Met 0	-	expression tag
Gly 1	-	expression tag
Arg 2	-	expression tag
Gly 3	-	expression tag
Ser 4	-	expression tag
Glu 5	-	expression tag
Phe 6	-	expression tag

E, G, L, N: 141 - 203 (UniProt: P60881)

PDB	External Database	Details
Gly 122	-	expression tag
Ser 123	-	expression tag
His 124	-	expression tag
Met 125	-	expression tag
Ala 126	-	expression tag
Ser 127	-	expression tag
Met 128	-	expression tag
Thr 129	-	expression tag
Gly 130	-	expression tag
Gly 131	-	expression tag
Gln 132	-	expression tag
Gln 133	-	expression tag
Met 134	-	expression tag
Gly 135	-	expression tag
Arg 136	-	expression tag
Gly 137	-	expression tag
Ser 138	-	expression tag
Glu 139	-	expression tag
Phe 140	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	14
	Total formula weight	191733.2
Non-Polymers*	Number of molecules	19
	Total formula weight	1125.6
All*	Total formula weight	192858.8

*Water molecules are not included.