5LA4
Crystal structure of apo human proheparanase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Heparanase | polymer | 509 | 57725.1 | 1 | UniProt (Q9Y251) Pfam (PF03662) | Homo sapiens (Human) | Endo-glucoronidase,Heparanase-1,Hpa1 |
| 2 | B (B) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 3 | C (C) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G86851RC) | |||
| 4 | D, E (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 5 | F, G, H, I, J (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 6 | K (A) | water | water | 18.0 | 218 | Chemie (HOH) |
Sequence modifications
A: 36 - 543 (UniProt: Q9Y251)
| PDB | External Database | Details |
|---|---|---|
| Gly 35 | - | expression tag |
| Arg 307 | Lys 307 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 57725.1 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 953.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 752.8 | |
| All* | Total formula weight | 59431.8 |
