5L8U
Crystal Structure of BAZ2B bromodomain in complex with 3-amino-2-methylpyridine derivative 5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain adjacent to zinc finger domain protein 2B | polymer | 116 | 13531.6 | 1 | UniProt (Q9UIF8) Pfam (PF00439) | Homo sapiens (Human) | hWALp4 |
| 2 | B (A) | ~{N}-[(1~{S})-1-(3,4-dihydro-2~{H}-1,5-benzodioxepin-7-yl)ethyl]-2-methyl-pyridin-3-amine | non-polymer | 284.4 | 1 | Chemie (6RS) PubChem (79042920) PubChem (122197576) | |||
| 3 | C, D (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
| 4 | E (A) | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A: 1858 - 1971 (UniProt: Q9UIF8)
| PDB | External Database | Details |
|---|---|---|
| Ser 1856 | - | expression tag |
| Met 1857 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13531.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 584.7 | |
| All* | Total formula weight | 14116.3 |
