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5L8H

Structure of USP46-UbVME

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Ubiquitin carboxyl-terminal hydrolase 46polymer35941725.41UniProt (P62068)
Pfam (PF00443)
Homo sapiens (Human)Deubiquitinating enzyme 46,Ubiquitin thioesterase 46,Ubiquitin-specific-processing protease 46
2B
(B)
Polyubiquitin-Bpolymer768618.91UniProt (P0CG47)
Pfam (PF00240)
Homo sapiens (Human)
3C
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
4D, E
(A, B)
waterwater18.0250Chemie (HOH)
Sequence modifications
A: 8 - 366 (UniProt: P62068)
PDBExternal DatabaseDetails
Val 46Cys 46conflict
Arg 265His 265conflict
B: 1 - 76 (UniProt: P0CG47)
PDBExternal DatabaseDetails
Gve 76Gly 76engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight50344.3
Non-Polymers*Number of molecules1
Total formula weight65.4
All*Total formula weight50409.7
*Water molecules are not included.

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PDB entries from 2025-08-06

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