5L7E
MCR IN COMPLEX WITH ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Mineralocorticoid receptor | polymer | 305 | 34832.8 | 1 | UniProt (P08235) Pfam (PF00104) In PDB | Homo sapiens (Human) | MR,Nuclear receptor subfamily 3 group C member 2 |
| 2 | B | NCOA1 peptide | polymer | 10 | 1173.4 | 1 | UniProt (by SIFTS) (Q15788) In PDB | Homo sapiens (Human) | |
| 3 | A | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID | non-polymer | 207.3 | 1 | Chemie (NHE) | |||
| 4 | A | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 5 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 7 | A | ~{N}-[[4-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]methyl]benzenesulfonamide | non-polymer | 342.4 | 1 | Chemie (6Q0) | |||
| 8 | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
A: 735 - 984 (UniProt: P08235)
| PDB | External Database | Details |
|---|---|---|
| Met 713 | - | initiating methionine |
| His 714 | - | expression tag |
| Asn 715 | - | expression tag |
| His 716 | - | expression tag |
| Asn 717 | - | expression tag |
| His 718 | - | expression tag |
| Asn 719 | - | expression tag |
| His 720 | - | expression tag |
| Asn 721 | - | expression tag |
| His 722 | - | expression tag |
| Asn 723 | - | expression tag |
| His 724 | - | expression tag |
| Asn 725 | - | expression tag |
| Gly 726 | - | expression tag |
| Gly 727 | - | expression tag |
| Glu 728 | - | expression tag |
| Asn 729 | - | expression tag |
| Leu 730 | - | expression tag |
| Tyr 731 | - | expression tag |
| Phe 732 | - | expression tag |
| Gln 733 | - | expression tag |
| Gly 734 | - | expression tag |
| Ser 808 | Cys 808 | conflict |
| Leu 810 | Ser 810 | conflict |
| Ser 910 | Cys 910 | conflict |
| Gly 985 | - | expression tag |
| Gly 986 | - | expression tag |
| Ser 987 | - | expression tag |
| Leu 988 | - | expression tag |
| Val 989 | - | expression tag |
| Pro 990 | - | expression tag |
| Arg 991 | - | expression tag |
| Gly 992 | - | expression tag |
| Ser 993 | - | expression tag |
| Gly 994 | - | expression tag |
| Gly 995 | - | expression tag |
| Gly 996 | - | expression tag |
| Ser 997 | - | expression tag |
| Gly 998 | - | expression tag |
| Gly 999 | - | expression tag |
| Ser 1000 | - | expression tag |
| Gly 1001 | - | expression tag |
| Gly 1002 | - | expression tag |
| Pro 1003 | - | expression tag |
| Gln 1004 | - | expression tag |
| Ala 1005 | - | expression tag |
| Gln 1006 | - | expression tag |
| Gln 1007 | - | expression tag |
| Lys 1008 | - | expression tag |
| Ser 1009 | - | expression tag |
| Leu 1010 | - | expression tag |
| Leu 1011 | - | expression tag |
| Gln 1012 | - | expression tag |
| Gln 1013 | - | expression tag |
| Leu 1014 | - | expression tag |
| Leu 1015 | - | expression tag |
| Thr 1016 | - | expression tag |
| Glu 1017 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36006.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 888.1 | |
| All* | Total formula weight | 36894.2 |
