5L7E
MCR IN COMPLEX WITH ligand
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue NHE A 1101 |
| Chain | Residue |
| A | GLU748 |
| A | ILE749 |
| A | VAL750 |
| A | TYR751 |
| A | LYS785 |
| A | HOH1224 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MPD A 1102 |
| Chain | Residue |
| A | GLN779 |
| A | LEU810 |
| A | LYS873 |
| A | GLU746 |
| A | PRO747 |
| A | GLN776 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 1103 |
| Chain | Residue |
| A | ARG861 |
| A | GLN923 |
| A | LYS926 |
| A | HOH1227 |
| A | HOH1292 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 1104 |
| Chain | Residue |
| A | GLN825 |
| A | PHE826 |
| A | GLU837 |
| A | MET840 |
| A | HIS853 |
| A | HOH1261 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 1105 |
| Chain | Residue |
| A | ARG904 |
| A | TRP918 |
| A | PHE921 |
| A | TYR922 |
| A | PHE946 |
| A | ARG947 |
| A | GLU948 |
| A | SER949 |
| A | HIS950 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | binding site for residue 6Q0 A 1106 |
| Chain | Residue |
| A | LEU769 |
| A | ASN770 |
| A | LEU772 |
| A | GLN776 |
| A | TRP806 |
| A | MET807 |
| A | LEU810 |
| A | SER811 |
| A | LEU814 |
| A | ARG817 |
| A | PHE829 |
| A | MET845 |
| A | PHE941 |
| A | CYS942 |
| A | HOH1255 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Region: {"description":"Important for coactivator binding"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15908963","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15967794","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YA3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AA5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AA6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15967794","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2AA5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AA6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Motif: {"description":"LXXLL motif 7"} |
| Chain | Residue | Details |
