5L0I
Human metavinculin MVt R975W cardiomyopathy-associated mutant (residues 959-1134)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Vinculin | polymer | 176 | 19648.7 | 1 | UniProt (P18206) Pfam (PF01044) | Homo sapiens (Human) | Metavinculin,MV |
| 2 | B (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | C (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | D (A) | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A: 959 - 1134 (UniProt: P18206)
| PDB | External Database | Details |
|---|---|---|
| Trp 975 | Arg 975 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19648.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 115.1 | |
| All* | Total formula weight | 19763.8 |
