5L01
Tryptophan 5-hydroxylase in complex with inhibitor (3~{S})-8-[2-azanyl-6-[(1~{R})-1-(4-chloranyl-2-phenyl-phenyl)-2,2,2-tris(fluoranyl)ethoxy]pyrimidin-4-yl]-2,8-diazaspiro[4.5]decane-3-carboxylic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tryptophan 5-hydroxylase 1 | polymer | 444 | 51061.1 | 1 | UniProt (P17752) Pfam (PF01842) Pfam (PF00351) | Homo sapiens (Human) | Tryptophan 5-monooxygenase 1 |
| 2 | B (A) | FE (III) ION | non-polymer | 55.8 | 1 | Chemie (FE) | |||
| 3 | C (A) | (3~{S})-8-[2-azanyl-6-[(1~{R})-1-(4-chloranyl-2-phenyl-phenyl)-2,2,2-tris(fluoranyl)ethoxy]pyrimidin-4-yl]-2,8-diazaspiro[4.5]decane-3-carboxylic acid | non-polymer | 562.0 | 1 | Chemie (6Z4) | |||
| 4 | D (A) | water | water | 18.0 | 141 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 51061.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 617.8 | |
| All* | Total formula weight | 51678.9 |
